journal article·2023-03Open access

Magneto‐Nanomechanical Array Biosensor for Ultrasensitive Detection of Oncogenic Exosomes for Early Diagnosis of Cancers (Small 9/2023)

Kainan Mei, Tianhao Yan, Yu Wang, Depeng Rao, Yongpei Peng, Wenjie Wu, Ye Chen, Min Ren, Jing Yang, Shangquan Wu, Qingchuan Zhang

Small· Volume 19· Issue 9

Abstract

Early Diagnosis of Cancers In article 2205445, Shangquan Wu, Qingchuan Zhang, and co-workers develop an ultra-sensitive nanomechanical sensor, which uses a magnetic-driven microcantilever array to selectively detect oncogenic exosomes. The magnetic force produces a far greater deflection of microcantilever than that produced by the intermolecular interaction force, even in the presence of very low concentrations of target substances. This method reduced the detection limit to less than 10 exosomes mL−1.
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Research context

OpenAlex topics: Photoacoustic and Ultrasonic Imaging

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Affiliations

CAS Key Laboratory of Mechanical Behavior and Design of Material Department of Modern Mechanics University of Science and Technology of China Hefei 230027 China

Department of Breast Surgery Department of General Surgery First Affiliated Hospital of Anhui Medical University Hefei 230022 China

References

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