DataVXSmallPaper
journal article·2022-02

Near‐Infrared Thermally Activated Delayed Fluorescence Nanoparticle: A Metal‐Free Photosensitizer for Two‐Photon‐Activated Photodynamic Therapy at the Cell and Small Animal Levels (Small 6/2022)

Fang Fang, Yi Yuan, Yingpeng Wan, Jing Li, Yueyue Song, Wen‐Cheng Chen, Dongxu Zhao, Yun Chi, Menglin Li, Chun‐Sing Lee, Jinfeng Zhang

Small· Volume 18· Issue 6
Publisher page
Source abstract

Abstract

Photodynamic Therapy In article number 2106215, Menglin Li, Jinfeng Zhang, and co-workers develop a metal-free photosensitizer (PS) based on thermally activated delayed fluorescence (TADF) nanoparticles, which demonstrates intrinsic two-photon-excited (TPE) property, near-infrared emissive fluorescence, and singlet oxygen generation ability. Moreover, the TPE-photodynamic therapy (PDT) performance and biosafety at the small animal level are investigated. This work provides a promising strategy to develop metal-free PSs and advances the potential clinical translations of TADF-based nanotherapeutics for high-precision bio-imaging and high-performance PDT.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Nanoplatforms for cancer theranostics · Photodynamic Therapy Research Studies · Advanced Nanomaterials in Catalysis

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Key Laboratory of Molecular Medicine and Biotherapy School of Life Sciences Beijing Institute of Technology Beijing 100081 P. R. China

Department of Materials Science and Engineering and Department of Chemistry City University of Hong Kong 83 Tat Chee Avenue, Kowloon Hong Kong SAR 999077 P. R. China

Center of Super‐Diamond and Advanced Films (COSDAF) and Department of Chemistry City University of Hong Kong 83 Tat Chee Avenue, Kowloon Hong Kong SAR 999077 P. R. China

Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing 100190 P. R. China

School of Chemical Engineering and Light Industry Guangdong University of Technology Guangzhou 510006 P. R. China

School of Materials Science and Engineering Beijing Institute of Technology Beijing 100081 P. R. China

References

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