Virus‐Like Particles: Switch from Polymorphic to Homogenous Self‐Assembly of Virus‐Like Particles of Simian Virus 40 through Double‐Cysteine Substitution (Small 45/2020)
Source abstract
Abstract
The polymorphism in the self-assembly of the capsid protein VP1 of simian virus 40 is eliminated through interfacial double-cysteine substitution, resulting in homogenous tiny virus-like particles with significantly enhanced structural stability. The findings presented by Gen-Quan Yin, Xian-En Zhang, Feng Li, and co-workers in article number 2004484 may be instructive for the development of biosynthetic protein nanomaterials.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Bacteriophages and microbial interactions
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Guangzhou Women and Children's Medical Center Guangzhou Medical University Guangzhou 510623 P. R. China
State Key Laboratory of Virology Wuhan Institute of Virology Center for Biosafety Mega‐Science Chinese Academy of Sciences (CAS) Wuhan 430071 P. R. China
College of Life Science University of Chinese Academy of Sciences Beijing 100049 P. R. China
National Laboratory of Biomacromolecules CAS Center for Excellence in Biomacromolecules Institute of Biophysics Chinese Academy of Sciences (CAS) Beijing 100101 P. R. China
References
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