Photobleaching: Improving the Sensitivity of Fluorescence‐Based Immunoassays by Photobleaching the Autofluorescence of Magnetic Beads (Small 3/2019)
Source abstract
Abstract
In fluorescence-based assays, the autofluorescence of capture surfaces produces strong background noise. In article number 1803751, Amos Danielli and co-workers use photobleaching as a method to reduce the autofluorescence of magnetic beads, a commonly used capture surface. The technique yields a 3-fold improvement in the limit of detection and signal-to-noise ratio of a fluorescence-based immunoassay.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Advanced Biosensing Techniques and Applications
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Affiliations
Faculty of Engineering Bar‐Ilan University Max and Anna Webb Street Ramat Gan 5290002 Israel
MagBiosense, Inc. 4320 Forest Park Ave., Suite 304 St. Louis MO 63108 USA
References
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