journal article·2023-10Open access

Aurozyme: A Revolutionary Nanozyme in Colitis, Switching Peroxidase‐Like to Catalase‐Like Activity (Small 41/2023)

Hyung Shik Kim, Sieun Lee, Dong Yun Lee

Small· Volume 19· Issue 41

Abstract

Aurozymes Aurozyme, a novel nanozyme, effectively treats inflammatory bowel disease (IBD). Composed of gold nanoparticles and glycyrrhizin with a glycol chitosan coating, it scavenges harmful radicals and molecular patterns in colitis. Aurozyme's unique catalase-like activity converts hydroxyl radicals to water and oxygen, reducing inflammation and promoting tissue repair. It also regulates gut microbiota, demonstrating its transformative potential for managing chronic inflammatory conditions. More details can be found in article number 2302331 by Dong Yun Lee and co-workers.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Advanced Nanomaterials in Catalysis · Nanoparticles: synthesis and applications · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Bioengineering College of Engineering, and BK FOUR Biopharmaceutical Innovation Leader for Education and Research Group Hanyang University Seoul 04763 Republic of Korea

Institute of Nano Science and Technology (INST) Hanyang University Seoul 04763 Republic of Korea

Institute for Bioengineering and Biopharmaceutical Research (IBBR) Hanyang University Seoul 04763 Republic of Korea

Elixir Pharmatech Inc. Seoul 07463 Republic of Korea

References

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