DataVXSmallPaper
journal article·2017-08Open access

2D Materials: Size Effect on the Cytotoxicity of Layered Black Phosphorus and Underlying Mechanisms (Small 32/2017)

Xuejiao Zhang, Ziming Zhang, Siyu Zhang, Dengyu Li, Wei Ma, ChuanXin Ma, Fengchang Wu, Qing Zhao, Qingfeng Yan, Baoshan Xing

Small· Volume 13· Issue 32
Publisher pageOpen full text
Source abstract

Abstract

Bulk black phosphorus (BP) crystals are synthesized and exfoliated into layered BP with different lateral size and thickness, in article number 1701210 by Qing Zhao, Qingfeng Yan, and Baoshan Xing, and co-workers. The results of real-time cell analysis (RTCA) display a concentration-, size-, and cell type-dependent cytotoxicity of layered BP. The cytotoxicity originates from the intracellular ROS generation and cell membrane disruption, but only the latter is related to size effect.
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Research context

Nanomaterials

OpenAlex topics: Nanoplatforms for cancer theranostics

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Affiliations

Key Laboratory of Pollution Ecology and Environmental Engineering Institute of Applied Ecology Chinese Academy of Sciences Shenyang 110016 China

Department of Chemistry Tsinghua University Beijing 100084 China

University of Chinese Academy of Sciences Beijing 100049 China

Stockbridge School of Agriculture University of Massachusetts Amherst MA 01003 USA

Department of Analytical Chemistry The Connecticut Agricultural Experiment Station New Haven CT 06504 USA

State Key Laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental Sciences Beijing 100012 China

References

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