Antibacterial Agents: Vacancy‐Induced Antibacterial Activity of XS_{2–}_{y} Quantum Dots against Drug‐Resistant Bacteria for Treatment of Bacterial Keratitis (Small 42/2020)

Huiyuan Li; Xiao Wang; Xiaofei Zhao; Guanhua Li; Fengyan Pei; Han Zhang; Yang Tan; Feng Chen

doi:10.1002/smll.202070230

journal article·2020-10Open access

Antibacterial Agents: Vacancy‐Induced Antibacterial Activity of XS_2–_y Quantum Dots against Drug‐Resistant Bacteria for Treatment of Bacterial Keratitis (Small 42/2020)

Huiyuan Li, Xiao Wang, Xiaofei Zhao, Guanhua Li, Fengyan Pei, Han Zhang, Yang Tan, Feng Chen

Small· Volume 16· Issue 42

Publisher page Open full text

Source abstract

Abstract

In article number 2004677, Han Zhang, Yang Tan, Feng Chen, and co-workers demonstrate that the antibacterial ability against drug-resistant bacteria can be endowed to transition metal dichalcogenides (XS2, X = Mo/W) quantum dots by sulfur vacancies, and their application in bacterial keratitis. The sulfur vacancies generated by the ion irradiation result in the one-way electron transport from the external environment to XS2, leading to a strong ROS-independent oxidative stress. For biomedical application against bacterial keratitis, it is observed that the occurrence of severe clinical manifestation like ocular perforation can be prevented.

Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis · Redox biology and oxidative stress

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Ophthalmology Jinan Central Hospital Cheeloo College of Medicine Shandong University Jinan Shandong 250012 China

Medical Laboratory Diagnosis Center Jinan Central Hospital Cheeloo College of Medicine Shandong University Jinan Shandong 250013 China

Department of Ophthalmology The Second Hospital Cheeloo College of Medicine Shandong University Jinan Shandong 250033 China

Department of Respiratory and Critical Care Medicine Jinan Central Hospital Cheeloo College of Medicine Shandong University Jinan Shandong 250013 China

School of Physics State Key Laboratory of Crystal Materials Shandong University Jinan Shandong 250100 China

References

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