journal article·2020-05Open access

Cerium Oxide Nanoparticles: Cerium Oxide Nanoparticles: Advances in Biodistribution, Toxicity, and Preclinical Exploration (Small 20/2020)

Eudald Casals, Muling Zeng, Marina Parra‐Robert, Guillermo Fernández‐Varo, Manuel Morales‐Ruiz, Wladimiro Jiménez, Víctor Puntes, Gregori Casals

Small· Volume 16· Issue 20

Abstract

The benefits of classic antioxidants can be translated to clinical therapies owing to the superior activity of CeO2 nanoparticles as redox buffers. In article number 1907322, Wladimiro Jiménez, Víctor Puntes, Gregori Casals, and co-workers present a historical background of their development for medicine, and analyze their pharmacokinetics, toxicity, and therapeutic value, focusing on the liver where they accumulate. Finally, considerations for medical nanoparticles to reach the clinic are discussed in detail.
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Research context

OpenAlex topics: Advanced Nanomaterials in Catalysis · Nanoparticle-Based Drug Delivery · Nanoparticles: synthesis and applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Biotechnology and Health Sciences Wuyi University Jiangmen 529020 China

Service of Biochemistry and Molecular Genetics Hospital Clinic Universitari Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) Barcelona 08036 Spain

Departament of Biomedicine University of Barcelona Barcelona 08036 Spain

Working Group for the Biochemical Assessment of Hepatic Disease‐SEQC ^{ML} Barcelona 08036 Spain

Vall d'Hebron Research Institute (VHIR) Barcelona 08035 Spain

Institut Català de Nanociència i Nanotecnologia (ICN2) CSIC The Barcelona Institute of Science and Technology (BIST) Campus UAB, Bellaterra Barcelona 08193 Spain

Institució Catalana de Recerca i Estudis Avançats (ICREA) Barcelona 08010 Spain

References

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