journal article·2015-10Open access

Tuberculosis: pH‐Responsive Isoniazid‐Loaded Nanoparticles Markedly Improve Tuberculosis Treatment in Mice (Small 38/2015)

Angela A. Hwang, Bai‐Yu Lee, Daniel L. Clemens, Barbara Jane Dillon, Jeffrey I. Zink, Marcus A. Horwitz

Small· Volume 11· Issue 38

Abstract

On page 5066, J. I. Zink, M. A. Horwitz, and co-workers use confocal microscopy to demonstrate the avid uptake of RITC-labeled mesoporous silica nanoparticles loaded with the anti-tuberculosis drug isoniazid (shown here in red) by human macrophages (nuclei stained blue with DAPI) infected with GFP-expressing Mycobacterium tuberculosis (shown here in green).
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Tuberculosis Research and Epidemiology

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Affiliations

Department of Chemistry and Biochemistry University of California Los Angeles 3013 Young Dr. East CA 90095‐1569 USA

Division of Infectious Diseases Department of Medicine University of California Los Angeles CHS 37‐121, 10833 Le Conte Ave. CA 90095‐1688 USA

California NanoSystems Institute University of California Los Angeles CA 90095‐8352 USA

References

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