Personalized Cancer Immunotherapy: Personalized Cancer Immunotherapy via Transporting Endogenous Tumor Antigens to Lymph Nodes Mediated by Nano Fe3O4 (Small 38/2018)
Source abstract
Abstract
In article number 1801372, Hongling Zhang, Zhenzhong Zhang, and co-workers show that, under local ultrasound treatment, nano Fe3O4 particles (∼10 nm) are released from Ce6/Fe3O4-L specifically within the tumor. Due to the excellent protein-bound efficiency and lymph node (LN)-targeting ability, endogenous tumor antigens are captured and transported to the LNs, thus potentiating cancer immunotherapy and providing personalized immunotherapy. The improved immune activation is synergistic with PD-L1 treatment.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Cancer Research and Treatments · Cancer Immunotherapy and Biomarkers
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Affiliations
School of Pharmaceutical Sciences Zhengzhou University Zhengzhou 450001 China
Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases Henan Province China
Collaborative Innovation Center of New Drug Research and Safety Evaluation Henan Province Zhengzhou 450001 China
References
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