journal article·2016-07

High‐Resolution Vertical Observation of Intracellular Structure Using Magnetically Responsive Microplates

Tetsuhiko Teshima, Hiroaki Onoe, Soichiro Tottori, Hiroka Aonuma, Takeomi Mizutani, Koki Kamiya, Hirotaka Ishihara, Hirotaka Kanuka, Shoji Takeuchi

Small· Volume 12· Issue 25
Publisher page

Abstract

A vertical confocal observation system capable of high-resolution observation of intracellular structure is demonstrated. The system consists of magnet-active microplates to rotate, incline, and translate single adherent cells in the applied magnetic field. Appended to conventional confocal microscopes, this system enables high-resolution cross-sectional imaging with single-molecule sensitivity in single scanning. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Research context

OpenAlex topics: Advanced Fluorescence Microscopy Techniques · Microfluidic and Bio-sensing Technologies · Advanced biosensing and bioanalysis techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Institute of Industrial Science The University of Tokyo 4‐6‐1 Komaba Meguro‐ku Tokyo 153‐8505 Japan

Department of Tropical Medicine The Jikei University School of Medicine 3‐25‐8 Nishi‐Shinbashi Minato‐ku Tokyo 105‐8461 Japan

Graduate School of Science Hokkaido University Kita 10 Nishi 8, Kita‐ku Sapporo Hokkaido 060‐0810 Japan

Kanagawa Academy of Science and Technology 3‐2‐1 Sakado Takatsu‐ku Kawasaki Kanagawa 213‐0012 Japan

Funding

Ministry of Education, Culture, Sports, Science, and Technology

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