A Generic Chemical Platform for Molecular Recognition and Stimuli‐Responsive Probes Based on Scanning Probe Microscopy

The grafting of poly-N-succinimidyl acrylate from scanning probe microscopy tips is shown to be a robust platform for the very easy elaboration of versatile probes with sensor capabilities and tunable properties. The modified tips (see image) can be easily postfunctionalized for single-molecule recognition of host–guest and ligand–receptor systems and for the design of smart probes that are thermo- and pH-responsive. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2296/2008/smll200700837_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.