Dynamic Re‐organization of Individual Adhesion Nanoclusters in Living Cells by Ligand‐Patterned Surfaces
Source abstract
Abstract
Ligand-patterned surfaces alter the spatio-temporal organization of specific receptors on the cell membrane. Chemically confined surfaces are fabricated using microcontact patterning. The dynamic re-organization of the integrin LFA-1 in living cells is monitored at the single-molecule level using total internal reflection fluorescence. The image on the left shows individual LFA-1 nanoclusters on a single cell being recruited to ligand-rich areas of the pattern.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Cell Adhesion Molecules Research · Nanofabrication and Lithography Techniques · Cellular Mechanics and Interactions
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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