article·2015-06-11

Silica Nanopills for Targeted Anticancer Drug Delivery

Marı́a Alba, Bahman Delalat, Pilar Formentı́n, Mary‐Louise Rogers, Lluı́s F. Marsal, Nicolas H. Voelcker

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Abstract

Multifunctional SiO2 microtubes for targeted drug delivery are produced with precise control over shape and size by combining lithography and electrochemical etching. The hollow core is loaded with a lipophilic anticancer drug generating nanopills and an antibody is conjugated to the external surface for cancer cell targeting. Results demonstrate selective killing of neuroblastoma cells that express the cognate receptor.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Silicon Nanostructures and Photoluminescence · Nanowire Synthesis and Applications · Carbon Nanotubes in Composites

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