Electrofluidic Lipid Membrane Biosensor

The electrical manipulation of a patterned lipid membrane is employed for the highly reliable, straightforward, and sensitive detection of membrane receptor–ligand interactions in an array platform. Target-binding modulates lipid fluidity and membrane phase, and the difference in membrane fluidity with different target concentrations is clearly distinguished in an amplifiable manner. This is achieved by locally concentrating charged, fluorescent lipids during electrophoresis. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.