journal article·2016-09Open access

Preparation of Well‐Defined DNA Samples for Reproducible Nanospectroscopic Measurements

Ewelina Lipiec, Aleksandre Japaridze, Jacek Szczerbiński, Giovanni Dietler, Renato Zenobi

Small· Volume 12· Issue 35

Abstract

Due to its well-defined topology and chemical structure, DNA could become a biological standard sample in the field of nanospectroscopy. Tip-enhanced Raman spectroscopy (TERS) provides new insights into individual DNA molecules immobilized on flat mica crystals. The high sensitivity of TERS is used to assess the chemical changes that appear in DNA upon different surface immobilization protocols. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Research context

OpenAlex topics: Advanced biosensing and bioanalysis techniques · Gold and Silver Nanoparticles Synthesis and Applications · Spectroscopy Techniques in Biomedical and Chemical Research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Laboratory of Organic Chemistry Department of Chemistry and Applied Biosciences ETH Zurich 8093 Zurich Switzerland

The Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences 31‐342 Krakow Poland

Laboratory of Physics of Living Matter Ecole Polytechnique Fédérale de Lausanne 1015 Lausanne Switzerland

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