Towards Rapid DNA Sequencing: Detecting Single‐Stranded DNA with a Solid‐State Nanopore

Small pores, big future! Methods to characterize and detect various types of DNA and their sequences continue to become more and more refined. Among many such studies, a recent paper has utilized a single nanopore, prepared from Si3N4 by using focused ion-beam milling techniques, located between two electrodes (see schematic). A potential applied across the electrodes causes DNA to pass through the pore, a process which can be regulated by varying conditions such as the pH of the system.