Vascular Electrical Stimulation with Wireless, Battery‐Free, and Fully Implantable Features Reduces Atherosclerotic Plaque Formation Through Sirt1‐Mediated Autophagy (Small 40/2023)

Pengyu Wang; Manman Li; Tielei Gao; Jiaying Fan; Dengfeng Zhang; Ying Zhao; Yajie Zhao; Yuqin Wang; Tianwei Guo; Xi Gao; Yujun Liu; Yang Gao; Xue Guan; Xinyong Sun; Jiyi Zhao; Hong Li; Liming Yang

doi:10.1002/smll.202370326

journal article·2023-10Open access

Vascular Electrical Stimulation with Wireless, Battery‐Free, and Fully Implantable Features Reduces Atherosclerotic Plaque Formation Through Sirt1‐Mediated Autophagy (Small 40/2023)

Pengyu Wang, Manman Li, Tielei Gao, Jiaying Fan, Dengfeng Zhang, Ying Zhao, Yajie Zhao, Yuqin Wang, Tianwei Guo, Xi Gao, Yujun Liu, Yang Gao, Xue Guan, Xinyong Sun, Jiyi Zhao, Hong Li, Liming Yang

Small· Volume 19· Issue 40

Publisher page Open full text

Source abstract

Abstract

Vascular Electrical Stimulations Hong Li, Liming Yang, and co-workers used battery-free implants and surgically mounted them on the abdominal aorta of high-fat-fed ApoE-/- mice, which were electrically stimulated using a wireless electrical stimulation device for four weeks to observe changes in atherosclerotic plaques. Direct vascular electrical stimulation has emerged as a promising therapeutic strategy for atherosclerosis by reducing atherosclerotic plaque formation through the activation of Sirt1/Atg5 pathway-mediated autophagy. More details can be found in article number 2300584.

Source: openalex_inverted_index · Quality: baseline

Research context

Energy storage Biomaterials

OpenAlex topics: Hydrogen's biological and therapeutic effects

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Basic Medical Sciences Harbin Medical University Harbin 150081 P. R. China

Department of Forensic Medicine Harbin Medical University Harbin 150081 P. R. China

Department of Pathology Harbin Medical University‐Daqing Daqing 163319 P. R. China

School of Basic Medical Sciences Harbin Medical University‐Daqing Daqing 163319 P. R. China

Department of Cardiology The First Affiliated Hospital of Harbin Medical University Harbin 150001 P. R. China

Cardiovascular Care Unit The First Affiliated Hospital of Harbin Medical University Harbin 150001 P. R. China

National Key Laboratory of Frigid Zone Cardiovascular Diseases (NKLFZCD) Harbin Medical University Harbin 150081 P. R. China

References

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