journal article·2024-06Open access

Microfluidic Impedance Cytometry Enabled One‐Step Sample Preparation for Efficient Single‐Cell Mass Spectrometry (Small 26/2024)

Junwen Zhu, Siyuan Pan, Huichao Chai, Peng Zhao, Yongxiang Feng, Zhen Cheng, Sichun Zhang, Wenhui Wang

Small· Volume 20· Issue 26

Abstract

Single-Cell Mass Spectrometry In article number 2310700, Wenhui Wang and co-workers proposed a one-step sample preparation strategy by leveraging label-free microfluidic impedance flow cytometry to solve the problem of simultaneous sorting and desalting of single cells. This strategy enables to flow mixed cell samples into the microfluidic chip, and then collect the target cell samples with desired size and electrical properties from the outlet for direct single cell mass spectrometry analysis.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Single-cell and spatial transcriptomics · Microfluidic and Bio-sensing Technologies

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Affiliations

State Key Laboratory of Precision Measurement Technology and Instrument Department of Precision Instrument Tsinghua University Beijing 100084 China

Department of Chemistry Tsinghua University Beijing 100084 China

Department of Automation Tsinghua University Beijing 100084 China

References

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