Bioassays: A Rapid and Label‐free SERS Detection Method for Biomarkers in Clinical Biofluids (Small 24/2014)
Source abstract
Abstract
W. K. Leong, M. Olivo, and co-workers show the use of a metal carbonyl-functionalized, nanostructured substrate in a rapid and simple assay for the detection of a potential biomarker for bladder cancer in clinical urine samples. On page 5030, changes in the carbonyl stretching vibrations, which lie in a spectral window free from interference from biomolecules, are monitored via SERS. This method is superior to current techniques, which typically involve multiple reagents and skilled handling, thus allowing SERS-based biomarker assays for clinical diagnosis.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Advanced Proteomics Techniques and Applications · Metabolomics and Mass Spectrometry Studies · Identification and Quantification in Food
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Affiliations
Singapore Bioimaging Consortium Agency for Science Technology and Research 138667 Singapore
Division of Chemistry & Biological Chemistry School of Physical & Mathematical Sciences Nanyang Technological University 21 Nanyang Link 637371 Singapore
Department of Urology Singapore General Hospital 169608 Singapore
School of Physics National University of Ireland Galway Ireland
References
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