Porous Matrix Stiffness Modulates Response to Targeted Therapy in Breast Carcinoma
Source abstract
Abstract
Porous matrix stiffness modulates response to targeted therapy. Poroelastic behavior within porous matrix may modulate the molecule events in cell-matrix and cell–cell interaction like the complex formation of human epidermal growth factor receptor-2 (HER2)-Src-α6β4 integrin, influencing the targeted therapy with lapatinib. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Cell Adhesion Molecules Research · Cellular Mechanics and Interactions · HER2/EGFR in Cancer Research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
National Center for Nanoscience and Technology Beijing 100190 P. R. China
Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences Beijing 100700 P. R. China
Institute of Biomedical Engineering Capital Medical University Beijing 100069 P. R. China
Funding
National Natural Science Foundation of China · Natural Science Foundation of Beijing Municipality
References (28)
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