journal article·2011-11-04

Artificial Cell Membrane‐Mimicking Nanostructure Facilitates Efficient Gene Delivery through Fusogenic Interaction with the Plasma Membrane of Living Cells

Sejin Son, Gahee Kim, Kaushik Singha, Samdae Park, Moonhor Ree, Won Jong Kim

Small· Volume 7· Issue 21
Publisher page

Abstract

A cell-membrane-mimicking nanostructure possesses amphipathic properties due to the presence of hydrophobic alkyl chains and polar phosphorylcholine groups. The distance between nanostructured multilayers resembles that of natural cell membranes. The self-assembled nanostructure has a strong affinity toward the natural cell membrane, and preloaded gene complex is delivered into cells through a fusogenic process.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: RNA Interference and Gene Delivery · Lipid Membrane Structure and Behavior · Advanced biosensing and bioanalysis techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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