journal article·2014-11Open access

Platelet‐Inspired Multiscaled Cytophilic Interfaces with High Specificity and Efficiency toward Point‐of‐Care Cancer Diagnosis

Xueli Liu, Feilong Zhang, Qian Wang, Jun Gao, Jingxin Meng, Shutao Wang, Zhenzhong Yang, Lei Jiang

Small· Volume 10· Issue 22

Abstract

Inspired by the interactions between platelets and tumor cells, multiscaled cytophilic interfaces are fabricated by assembling platelet-mimicking microspheres via oxidative polymerization of polyaniline nanohairs through transverse nanochannels in the shells of hollow polystyrene microspheres, and modifying specific recognition molecules. This interface realizes efficient tumor-cell recognition and isolation from artificial blood, suggesting a new platform for metastasis diagnosis and cancer treatment. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Polymer Surface Interaction Studies · Nanoparticle-Based Drug Delivery · Advancements in Transdermal Drug Delivery

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Beijing National Laboratory for Molecular Sciences (BNLMS) Key Laboratory of Organic Solids Institute of Chemistry Chinese Academy of Sciences Beijing 100190 PR China

University of Chinese Academy of Sciences Beijing 100049 PR China

Laboratory of Bio‐inspired Smart Interface Science Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing 100190 PR China

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