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journal article·2009-12-18

Quantitative CARS Microscopic Detection of Analytes and Their Isotopomers in a Two‐Channel Microfluidic Chip

Gero Bergner, Susana Chatzipapadopoulos, Denis Akimov, Benjamin Dietzek, Daniéll Malsch, Thomas Henkel, Sebastian Schlücker, Jürgen Popp

Small· Volume 5· Issue 24
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Source abstract

Abstract

Fast and quantitative detection of organic analytes is achieved by coherent anti-Stokes Raman scattering (CARS) microscopy using a two-channel microfluidic chip in combination with deuterated isotopomers as a reference (see picture). This experimental design enables the simultaneous measurement of both the chemically relevant Raman-resonant signal and the non-Raman-resonant background.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Spectroscopy Techniques in Biomedical and Chemical Research · Spectroscopy and Chemometric Analyses · Protein Interaction Studies and Fluorescence Analysis

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (21)

Show source-provided references
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15. For details on image processing see the Supporting Information.
16. Using a second‐order polynomial with a variable vertical offset one obtains${{I_{{\rm C}\rm 7 {\rm D}\rm 8 {\rm /C}\rm 7 {\rm H}\rm 8 } } \over {I_{{\rm C}\rm 7 {\rm H}\rm 8 } }} = 1.058 + 0.169x_{{\rm C}\rm 7 {\rm D}\rm 8 } + 1.012x_{{\rm C}\rm 7 {\rm D}_8 }^2$.
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18. The calculation is shown in the Supporting Information.
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