Inherent Capability of Self‐Assembling Nanostructures in Specific Proteasome Activation for Cancer Cell Pyroptosis (Small 9/2023)
Source abstract
Abstract
Cancer Cell Pyroptosis In article number 2205531, Ke-Wu Zeng and co-workers describe the natural product oleanolic acid-based self-assembling nanostructures specially bind to proteasome subunit alpha 6 (PSMA6) to activate proteasome for cancer cell pyroptosis. This study opens up a new direction for the development anti-cancer nanomedicine from natural resources.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Peptidase Inhibition and Analysis · Advanced Nanomaterials in Catalysis · Ubiquitin and proteasome pathways
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical Sciences Peking University Beijing 100191 China
Proteomics Laboratory Medical and Healthy Analytical Center Peking University Health Science Center Beijing 100191 China
References
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