Phenome–Genome Profiling: Phenome–Genome Profiling of Single Bacterial Cell by Raman‐Activated Gravity‐Driven Encapsulation and Sequencing (Small 30/2020)
Source abstract
Abstract
In article number 2001172, Jian Xu, Bo Ma, and co-workers invent Raman-activated gravity-driven single-cell encapsulation and sequencing (RAGE-Seq). It produces antimicrobial susceptibility phenotypes and the genome sequence of 99.5% coverage simultaneously from precisely one bacterial cell. The ability to profile and correlate the microbial metabolic phenome and high-quality genomes at one-cell resolution has broad implications in clinical medicine.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Spectroscopy Techniques in Biomedical and Chemical Research
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Affiliations
Single‐Cell Center CAS Key Laboratory of Biofuels Shandong Key Laboratory of Energy Genetics and Shandong Institute of Energy Research Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of Sciences Qingdao Shandong 266101 China
Laboratory for Marine Biology and Biotechnology Qingdao National Laboratory for Marine Science and Technology Qingdao Shandong 266071 China
University of Chinese Academy of Sciences Beijing 100049 China
References
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