journal article·2024-07Open access

Nanosafety: a Perspective on Nano‐Bio Interactions

Bengt Fadeel, Arturo A. Keller

Small· Volume 20· Issue 28

Abstract

Abstract Engineered nanomaterials offer numerous benefits to society ranging from environmental remediation to biomedical applications such as drug or vaccine delivery as well as clean and cost‐effective energy production and storage, and the promise of a more sustainable way of life. However, as nanomaterials of increasing sophistication enter the market, close attention to potential adverse effects on human health and the environment is needed. Here a critical perspective on nanotoxicological research is provided; the authors argue that it is time to leverage the knowledge regarding the biological interactions of nanomaterials to achieve a more comprehensive understanding of the human health and environmental impacts of these materials. Moreover, it is posited that nanomaterials behave like biological entities and that they should be regulated as such.
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Research context

OpenAlex topics: Nanoparticles: synthesis and applications · Healthcare and Environmental Waste Management · Air Quality and Health Impacts

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Institute of Environmental Medicine Karolinska Institutet 17177 Stockholm Sweden

Bren School of Environmental Science & Management University of California Santa Barbara California CA 93106 USA

Funding

Stiftelsen för Miljöstrategisk Forskning · Vetenskapsrådet

References (75)

Show source-provided references
1. 10.1038/s41565-023-01409-z10.1038/s41565-023-01409-z ↗
2. 10.1126/science.aad076810.1126/science.aad0768 ↗
3. 10.1002/anie.20140336710.1002/anie.201403367 ↗
4. 10.1002/smll.20200098010.1002/smll.202000980 ↗
5. 10.1021/acsnano.2c0012810.1021/acsnano.2c00128 ↗
6. 10.1126/science.111439710.1126/science.1114397 ↗
7. 10.1002/smll.20070059510.1002/smll.200700595 ↗
8. 10.1002/anie.20100103710.1002/anie.201001037 ↗
9. 10.1002/smll.20110000110.1002/smll.201100001 ↗
10. 10.1126/science.aau829910.1126/science.aau8299 ↗
11. 10.1038/nnano.2008.11110.1038/nnano.2008.111 ↗
12. 10.1021/acsnano.8b0360410.1021/acsnano.8b03604 ↗
13. 10.1021/nl802315h10.1021/nl802315h ↗
14. 10.1038/nnano.2010.4410.1038/nnano.2010.44 ↗
15. 10.1080/10408444.2016.120606110.1080/10408444.2016.1206061 ↗
16. 10.1038/s41565-019-0613-910.1038/s41565-019-0613-9 ↗
17. 10.1016/j.cub.2017.09.00710.1016/j.cub.2017.09.007 ↗
18. 10.1038/s41565-020-0654-010.1038/s41565-020-0654-0 ↗
19. 10.1038/s41565-020-0656-y10.1038/s41565-020-0656-y ↗
20. 10.1002/anie.20120766410.1002/anie.201207664 ↗
21. 10.1002/anie.20120199110.1002/anie.201201991 ↗
22. 10.1038/nnano.2008.6810.1038/nnano.2008.68 ↗
23. 10.1002/smll.20120146310.1002/smll.201201463 ↗
24. 10.1021/acsnano.6b0855110.1021/acsnano.6b08551 ↗
25. 10.1021/nn403256v10.1021/nn403256v ↗
26. 10.1038/nbt.169610.1038/nbt.1696 ↗
27. 10.1002/adma.20200391310.1002/adma.202003913 ↗
28. 10.1021/nl201121410.1021/nl2011214 ↗
29. 10.1021/nn500911610.1021/nn5009116 ↗
30. 10.1016/j.addr.2022.11442210.1016/j.addr.2022.114422 ↗
31. 10.1016/j.celrep.2021.10873410.1016/j.celrep.2021.108734 ↗
32. 10.1038/s41565-023-01363-w10.1038/s41565-023-01363-w ↗
33. 10.1038/s41586-021-04243-210.1038/s41586-021-04243-2 ↗
34. 10.1039/D3NH00124E10.1039/D3NH00124E ↗
35. 10.1016/j.cell.2023.04.02510.1016/j.cell.2023.04.025 ↗
36. 10.1073/pnas.080393310510.1073/pnas.0803933105 ↗
37. 10.1126/science.115699510.1126/science.1156995 ↗
38. 10.1038/ni.163110.1038/ni.1631 ↗
39. 10.1073/pnas.100815510710.1073/pnas.1008155107 ↗
40. 10.1021/nn200595c10.1021/nn200595c ↗
41. 10.1021/acsnano.3c0560010.1021/acsnano.3c05600 ↗
42. 10.1016/j.xcrm.2022.10089910.1016/j.xcrm.2022.100899 ↗
43. 10.1021/acsnano.1c0590110.1021/acsnano.1c05901 ↗
44. 10.1021/nn201950e10.1021/nn201950e ↗
45. 10.1021/nn406018q10.1021/nn406018q ↗
46. 10.1038/s41467-023-35902-910.1038/s41467-023-35902-9 ↗
47. 10.1038/s41565-021-00924-110.1038/s41565-021-00924-1 ↗
48. 10.1038/s41467-021-21164-w10.1038/s41467-021-21164-w ↗
49. 10.1038/s41578-023-00552-210.1038/s41578-023-00552-2 ↗
50. 10.1038/s41589-022-01093-510.1038/s41589-022-01093-5 ↗
51. 10.1002/wnan.179810.1002/wnan.1798 ↗
52. 10.1002/anie.20090668410.1002/anie.200906684 ↗
53. 10.1038/s41565-021-00856-w10.1038/s41565-021-00856-w ↗
54. 10.1038/s41565-021-00914-310.1038/s41565-021-00914-3 ↗
55. 10.1021/nn303449n10.1021/nn303449n ↗
56. 10.1021/nn403080y10.1021/nn403080y ↗
57. 10.1056/NEJMra160026610.1056/NEJMra1600266 ↗
58. 10.1038/s41565-022-01260-810.1038/s41565-022-01260-8 ↗
59. 10.1186/s12989-021-00410-510.1186/s12989-021-00410-5 ↗
60. 10.1186/s12989-023-00528-810.1186/s12989-023-00528-8 ↗
61. 10.1038/s41565-018-0231-y10.1038/s41565-018-0231-y ↗
62. 10.1021/acs.est.2c0703910.1021/acs.est.2c07039 ↗
63. 10.1038/s41565-019-0461-710.1038/s41565-019-0461-7 ↗
64. 10.1016/B978-0-12-822425-0.00041-510.1016/B978-0-12-822425-0.00041-5 ↗
65. 10.1038/s41565-022-01226-w10.1038/s41565-022-01226-w ↗
66. 10.1172/JCI6689510.1172/JCI66895 ↗
67. 10.1016/j.taap.2015.09.01910.1016/j.taap.2015.09.019 ↗
68. 10.1016/j.taap.2017.04.01910.1016/j.taap.2017.04.019 ↗
69. 10.1096/fj.201700187R10.1096/fj.201700187R ↗
70. 10.1016/j.cotox.2023.10042910.1016/j.cotox.2023.100429 ↗
71. 10.1002/smll.20190766310.1002/smll.201907663 ↗
72. 10.1038/s41565-018-0185-010.1038/s41565-018-0185-0 ↗
73. 10.1038/s41565-022-01096-210.1038/s41565-022-01096-2 ↗
74. 10.1038/s41565-023-01393-410.1038/s41565-023-01393-4 ↗
75. 10.1038/s41565-022-01173-610.1038/s41565-022-01173-6 ↗