journal article·2023-01

Rational Design of Soft–Hard Interfaces through Bioinspired Engineering

Hui Zhang, Yufei Ma, Yijie Wang, Lin Niu, Rui Zou, Min Zhang, Hao Liu, Guy M. Genin, Ang Li, Feng Xu

Small· Volume 19· Issue 1
Publisher page

Abstract

Abstract Soft–hard tissue interfaces in nature present a diversity of hierarchical transitions in composition and structure to address the challenge of stress concentrations that would otherwise arise at their interface. The translation of these into engineered materials holds promise for improved function of biomedical interfaces. Here, soft–hard tissue interfaces found in the body in health and disease, and the application of the diverse, functionally graded, and hierarchical structures that they present to bioinspired engineering materials are reviewed. A range of such bioinspired engineering materials and associated manufacturing technologies that are on the horizon in interfacial tissue engineering, hydrogel bioadhesion at the interfaces, and healthcare and medical devices are described.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · Bone Tissue Engineering Materials · Advanced Sensor and Energy Harvesting Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research College of Stomatology Xi'an Jiaotong University Xi'an 710004 P. R. China

The Key Laboratory of Biomedical Information Engineering of Ministry of Education School of Life Science and Technology Xi'an Jiaotong University Xi'an 710049 P. R. China

Bioinspired Engineering and Biomechanics Center (BEBC) Xi'an Jiaotong University Xi'an 710049 P. R. China

State Key Laboratory of Military Stomatology Department of General Dentistry and Emergency School of Stomatology Fourth Military Medical University Xi'an 710032 P. R. China

Department of Mechanical Engineering & Materials Science Washington University in St. Louis St. Louis MO 63130 USA

NSF Science and Technology Center for Engineering MechanoBiology Washington University in St. Louis St. Louis MO 63130 USA

Funding

National Natural Science Foundation of China · Natural Science Foundation of Shaanxi Province · National Institutes of Health

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