journal article·2011-07-18

Influence of Nanostructure Morphology on Host Capacity and Kinetics of Guest Release

Nam S. Lee, Lily Yun Lin, William L. Neumann, John N. Freskos, Amolkumar Karwa, Jeng J. Shieh, Richard B. Dorshow, Karen L. Wooley

Small· Volume 7· Issue 14
Publisher page

Abstract

Morphology-dependent drug loading capacities and release kinetics are observed from pH-responsive diblock copolymer-based nano-objects, derived from the same block copolymer precursor. Shell-crosslinked, rod-shaped nanostructures exhibit a higher doxorubicin-loading capacity and rate of release than do their spherical counterparts. The extent of crosslinking and the type of crosslinker is also demonstrated to affect the rate of release.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Advanced Polymer Synthesis and Characterization · Nanoparticle-Based Drug Delivery · Polymer Surface Interaction Studies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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