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journal article·2021-12

Molecular Engineering of Laser‐Induced Graphene for Potential‐Driven Broad‐Spectrum Antimicrobial and Antiviral Applications

Meijia Gu, Libei Huang, Zhaoyu Wang, Weihua Guo, Le Cheng, Yuncong Yuan, Zhou Zhou, Liu Hu, Sijie Chen, Chao Shen, Ben Zhong Tang, Ruquan Ye

Small· Volume 17· Issue 51
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Source abstract

Abstract

Abstract Worldwide, countless deaths have been caused by the coronavirus disease 2019. In addition to the virus variants, an increasing number of fatal fungal infections have been reported, which further exacerbates the scenario. Therefore, the development of porous surfaces with both antiviral and antimicrobial capacities is of urgent need. Here, a cost‐effective, nontoxic, and metal‐free strategy is reported for the surface engineering of laser‐induced graphene (LIG). The authors covalently engineer the surface potential of the LIG from −14 to ≈+35 mV (LIG+), enabling both high‐efficiency antimicrobial and antiviral performance under mild conditions. Specifically, several candidate microorganisms of different types, includingEscherichia coli,Streptomyces tenebrarius, andCandida albicans, are almost completely inactivated after 10‐min solar irradiation. LIG+also exhibits a strong antiviral effect against human coronaviruses: 99% HCoV‐OC43 and 100% HCoV‐229E inactivation are achieved after 20‐min treatment. Such enhancement may also be observed against other types of pathogens that are heat‐sensitive and oppositely charged. Besides, the covalent modification strategy alleviates the leaching problem, and the low cytotoxicity of LIG+makes it advantageous. This study highlights the synergy of surface potential and photothermal effect in the inactivation of pathogens and it provides a direction for designing porous materials for airborne disease removal and water disinfection.
Source: crossref · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Graphene and Nanomaterials Applications · Nanoplatforms for cancer theranostics · Advanced Sensor and Energy Harvesting Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Key Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of Education School of Pharmaceutical Sciences Wuhan University Wuhan Hubei 430071 China

Department of Chemistry City University of Hong Kong Kowloon Hong Kong 999077 China

Department of Chemistry Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction and Institute for Advanced Study The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong 999077 China

College of Life Sciences Wuhan University Wuhan Hubei 430072 China

Ming Wai Lau Center for Reparative Medicine Karolinska Institute Sha Tin Hong Kong 999077 China

China Center for Type Culture Collection Wuhan University Wuhan Hubei 430072 China

Shenzhen Institute of Molecular Aggregate Science and Engineering School of Science and Engineering The Chinese University of Hong Kong Longgang District Shenzhen Guangdong 518172 China

Center for Aggregation‐Induced Emission State Key Laboratory of Luminescent Materials and Devices SCUT‐HKUST Joint Research Institute South China University of Technology Tianhe Qu Guangzhou Guangdong 510640 China

State Key Laboratory of Marine Pollution City University of Hong Kong Kowloon Hong Kong 999077 China

City University of Hong Kong Shenzhen Research Institute Shenzhen Guangdong 518057 China

Funding

National Natural Science Foundation of China

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