journal article·2022-06-28

Infant Skin Friendly Adhesive Hydrogel Patch Activated at Body Temperature for Bioelectronics Securing and Diabetic Wound Healing

Yanan Jiang, Xin Zhang, Wei Zhang, Menghao Wang, Liwei Yan, Kefeng Wang, Lu Han, Xiong Lu

ACS Nano· Volume 16· Issue 6
Publisher page

Abstract

Adhesive-caused injury is a great threat for infants with premature skin or diabetic patients with fragile skin because extra-strong adhesion might incur pain, inflammation, and exacerbate trauma upon removal. Herein, we present a skin-friendly adhesive hydrogel patch based on protein-polyphenol complexation strategy, which leads to a thermoresponsive network sensitive to body temperature. The adhesion of the hydrogel is smartly activated after contacting with warm skin, whereas the painless detachment is easily realized by placing an ice bag on the surface of the hydrogel. The hydrogel exhibits an immunomodulatory performance that prevents irritation and allergic reactions during long-period contact with the skin. Thus, the hydrogel patch works as a conformable and nonirritating interface to guarantee nondestructively securing bioelectronics on infant skin for healthcare. Furthermore, the hydrogel patch provides gentle adhesion to wounded skin and provides a favorable environment to speed up the healing process for managing diabetic wounds.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Advanced Sensor and Energy Harvesting Materials · Wound Healing and Treatments · Electrospun Nanofibers in Biomedical Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Materials Science and Engineering, Key Lab of Advanced Technologies of Materials, Ministry of Education, Yibin Institute of Southwest Jiaotong University, Southwest Jiaotong University, Chengdu 610031, Sichuan, China

Department of Chemistry, Southern University of Science and Technology, Shenzhen 518055, Guangdong, China

National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, Sichuan, China

School of Medicine and Pharmaceutics, Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology, Ocean University of China, Qingdao 266003, Shandong, China

Funding

Guangdong Science and Technology Department · Central University Basic Research Fund of China · National Natural Science Foundation of China · Shenzhen Funds of the Central Government to Guide Local Scientific and Technological Development · Sichuan Key Research and Development Program of China · Pilot (Qingdao) National Laboratory for Marine Science and Technology

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