journal article·2020-06-23

Emerging Implantable Energy Harvesters and Self-Powered Implantable Medical Electronics

Dongjie Jiang, Bojing Shi, Han Ouyang, Yubo Fan, Zhong Lin Wang, Zhou Li

ACS Nano· Volume 14· Issue 6
Publisher page

Abstract

Implantable energy harvesters (IEHs) are the crucial component for self-powered devices. By harvesting energy from organisms such as heartbeat, respiration, and chemical energy from the redox reaction of glucose, IEHs are utilized as the power source of implantable medical electronics. In this review, we summarize the IEHs and self-powered implantable medical electronics (SIMEs). The typical IEHs are nanogenerators, biofuel cells, electromagnetic generators, and transcutaneous energy harvesting devices that are based on ultrasonic or optical energy. A benefit from these technologies of energy harvesting in vivo, SIMEs emerged, including cardiac pacemakers, nerve/muscle stimulators, and physiological sensors. We provide perspectives on the challenges and potential solutions associated with IEHs and SIMEs. Beyond the energy issue, we highlight the implanted devices that show the therapeutic function in vivo.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Advanced Sensor and Energy Harvesting Materials · Energy Harvesting in Wireless Networks · Wireless Power Transfer Systems

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

CAS Center for Excellence in Nanoscience, Beijing Key Laboratory of Micro-nano Energy and Sensor, Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 100083, China

School of Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing 100049, China

Beijing Advanced Innovation Centre for Biomedical Engineering, Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China

School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States

Center on Nanoenergy Research, School of Physical Science and Technology, Guangxi University, Nanning 530004, China

Funding

State Administration of Foreign Experts Affairs · University of Chinese Academy of Sciences · Ministry of Education of the People's Republic of China · Ministry of Science and Technology of the People's Republic of China · Natural Science Foundation of Beijing Municipality · China Postdoctoral Science Foundation · Ministry of Human Resources and Social Security · National Natural Science Foundation of China · Central Committee of the Communist Party of China

References (97)

Show source-provided references
1. 10.1038/528026a10.1038/528026a ↗
2. 10.1073/pnas.190985011610.1073/pnas.1909850116 ↗
3. 10.1021/acsnano.5b0485510.1021/acsnano.5b04855 ↗
4. 10.1146/annurev-bioeng-071516-04451710.1146/annurev-bioeng-071516-044517 ↗
5. 10.1002/aenm.20170121010.1002/aenm.201701210 ↗
6. 10.1021/acs.chemrev.9b0011510.1021/acs.chemrev.9b00115 ↗
7. 10.1038/s41578-018-0070-310.1038/s41578-018-0070-3 ↗
8. 10.1016/j.rser.2017.10.10210.1016/j.rser.2017.10.102 ↗
9. 10.1002/adma.20180151110.1002/adma.201801511 ↗
10. Parsonnet V. · ASAIO J. · 1963 · 9 · 174
11. 10.1371/journal.pone.001047610.1371/journal.pone.0010476 ↗
12. 10.1002/adma.20140206410.1002/adma.201402064 ↗
13. 10.1088/0964-1726/25/12/12300110.1088/0964-1726/25/12/123001 ↗
14. 10.1002/adfm.20180882010.1002/adfm.201808820 ↗
15. 10.1016/j.nanoen.2019.10403910.1016/j.nanoen.2019.104039 ↗
16. 10.1016/j.mtener.2020.10038610.1016/j.mtener.2020.100386 ↗
17. 10.1002/inf2.1206410.1002/inf2.12064 ↗
18. 10.1016/j.elecom.2013.09.02110.1016/j.elecom.2013.09.021 ↗
19. 10.1007/BF0251331510.1007/BF02513315 ↗
20. 10.1143/JJAP.40.386510.1143/JJAP.40.3865 ↗
21. 10.1007/s00417-004-0909-810.1007/s00417-004-0909-8 ↗
22. 10.1038/s41551-016-002210.1038/s41551-016-0022 ↗
23. 10.1126/science.aan399710.1126/science.aan3997 ↗
24. 10.1002/inf2.1210310.1002/inf2.12103 ↗
25. 10.1002/aenm.20190187510.1002/aenm.201901875 ↗
26. 10.1002/adfm.20180864010.1002/adfm.201808640 ↗
27. 10.1038/s41467-019-10433-410.1038/s41467-019-10433-4 ↗
28. 10.1002/adfm.20170380110.1002/adfm.201703801 ↗
29. 10.1016/j.nanoen.2018.12.06910.1016/j.nanoen.2018.12.069 ↗
30. 10.1063/1.507418410.1063/1.5074184 ↗
31. 10.1038/nnano.2008.31410.1038/nnano.2008.314 ↗
32. 10.1002/adhm.20170129810.1002/adhm.201701298 ↗
33. 10.1126/science.112400510.1126/science.1124005 ↗
34. 10.1002/adma.20090435510.1002/adma.200904355 ↗
35. 10.1073/pnas.131723311110.1073/pnas.1317233111 ↗
36. 10.1016/j.nanoen.2016.02.03710.1016/j.nanoen.2016.02.037 ↗
37. 10.1063/1.497680310.1063/1.4976803 ↗
38. 10.1016/j.nanoen.2017.11.02310.1016/j.nanoen.2017.11.023 ↗
39. 10.1007/s40820-017-0185-x10.1007/s40820-017-0185-x ↗
40. 10.1109/TBCAS.2018.286540510.1109/TBCAS.2018.2865405 ↗
41. 10.1038/s41928-018-0189-710.1038/s41928-018-0189-7 ↗
42. 10.1002/adfm.20170034110.1002/adfm.201700341 ↗
43. 10.1016/j.mattod.2016.12.00110.1016/j.mattod.2016.12.001 ↗
44. 10.1016/j.nanoen.2018.10.07810.1016/j.nanoen.2018.10.078 ↗
45. 10.1002/adma.20160670310.1002/adma.201606703 ↗
46. 10.1016/j.nanoen.2012.01.00410.1016/j.nanoen.2012.01.004 ↗
47. 10.1016/j.mattod.2019.05.01610.1016/j.mattod.2019.05.016 ↗
48. 10.1021/acsnano.6b0020010.1021/acsnano.6b00200 ↗
49. 10.1016/j.nanoen.2018.02.03010.1016/j.nanoen.2018.02.030 ↗
50. 10.1002/adma.20150335610.1002/adma.201503356 ↗
51. 10.1038/s41467-019-09851-110.1038/s41467-019-09851-1 ↗
52. 10.1021/nl503402c10.1021/nl503402c ↗
53. 10.1016/j.nanoen.2016.08.02410.1016/j.nanoen.2016.08.024 ↗
54. 10.1021/acsnano.6b0269310.1021/acsnano.6b02693 ↗
55. 10.1021/acsnano.9b0223310.1021/acsnano.9b02233 ↗
56. 10.1126/sciadv.150147810.1126/sciadv.1501478 ↗
57. 10.1073/pnas.171087411510.1073/pnas.1710874115 ↗
58. 10.1002/adma.20180189510.1002/adma.201801895 ↗
59. 10.1016/j.nanoen.2018.10.02010.1016/j.nanoen.2018.10.020 ↗
60. 10.1007/s10439-012-0623-310.1007/s10439-012-0623-3 ↗
61. 10.1109/TBCAS.2016.258065810.1109/TBCAS.2016.2580658 ↗
62. 10.1016/j.hrthm.2016.10.01610.1016/j.hrthm.2016.10.016 ↗
63. 10.1109/TBME.2017.277356810.1109/TBME.2017.2773568 ↗
64. 10.1109/TBME.2019.293202810.1109/TBME.2019.2932028 ↗
65. 10.1038/s41586-018-0823-610.1038/s41586-018-0823-6 ↗
66. 10.1186/s12984-019-0501-410.1186/s12984-019-0501-4 ↗
67. 10.1038/s41598-019-38554-210.1038/s41598-019-38554-2 ↗
68. Kang, C.; Chang, T. C.; Vo, J.; Charthad, J.; Weber, M.; Arbabian, A.; Vasudevan, S. Long-Term In Vivo Performance of Novel Ultrasound Powered Implantable Devices. Proceedings of the 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Honolulu, HI, July 18–21, 2018; IEEE: Piscataway, NJ, 2018; pp 2985–2988.10.1109/EMBC.2018.8512978 ↗
69. 10.1016/j.hrthm.2015.02.03210.1016/j.hrthm.2015.02.032 ↗
70. 10.1002/adhm.20160022210.1002/adhm.201600222 ↗
71. 10.18494/SAM.2018.166410.18494/SAM.2018.1664 ↗
72. 10.1039/c1ee02200h10.1039/c1ee02200h ↗
73. 10.1021/ja210794c10.1021/ja210794c ↗
74. 10.1039/C4EE03430A10.1039/C4EE03430A ↗
75. 10.1016/j.bios.2015.11.07710.1016/j.bios.2015.11.077 ↗
76. 10.1021/ja211714w10.1021/ja211714w ↗
77. 10.1039/c2ee21626d10.1039/c2ee21626d ↗
78. 10.1039/C2EE23209J10.1039/C2EE23209J ↗
79. 10.1002/elan.20130013610.1002/elan.201300136 ↗
80. 10.1002/cphc.20190070010.1002/cphc.201900700 ↗
81. 10.1038/nbt.239410.1038/nbt.2394 ↗
82. 10.1016/j.jacc.2016.10.06110.1016/j.jacc.2016.10.061 ↗
83. 10.1016/j.jacc.2016.10.06410.1016/j.jacc.2016.10.064 ↗
84. 10.1007/s10439-013-0887-210.1007/s10439-013-0887-2 ↗
85. 10.1039/c3cp50929j10.1039/c3cp50929j ↗
86. 10.1002/adma.20140056210.1002/adma.201400562 ↗
87. 10.1021/nl300972f10.1021/nl300972f ↗
88. 10.1039/C5EE01593F10.1039/C5EE01593F ↗
89. 10.1016/j.nanoen.2013.12.01610.1016/j.nanoen.2013.12.016 ↗
90. 10.1016/j.nanoen.2018.04.00410.1016/j.nanoen.2018.04.004 ↗
91. 10.1038/s41467-018-07764-z10.1038/s41467-018-07764-z ↗
92. 10.1002/advs.20190014910.1002/advs.201900149 ↗
93. 10.1016/j.nanoen.2019.06.04010.1016/j.nanoen.2019.06.040 ↗
94. 10.1002/adfm.20180756010.1002/adfm.201807560 ↗
95. 10.1021/acs.nanolett.6b0196810.1021/acs.nanolett.6b01968 ↗
96. 10.1021/acsnano.8b0030310.1021/acsnano.8b00303 ↗
97. 10.1038/s41586-019-1710-510.1038/s41586-019-1710-5 ↗