journal article·2018-11-27Open access

Safety Assessment of Graphene-Based Materials: Focus on Human Health and the Environment

Bengt Fadeel, Cyrill Bussy, Sonia Merino, Ester Vázquez, Emmanuel Flahaut, Florence Mouchet, Lauris Evariste, Laury Gauthier, Antti J. Koivisto, Ulla Vogel, Cristina Martín, Lucia G. Delogu, Tina Buerki-Thurnherr, Peter Wick, Didier Beloin-Saint-Pierre, Roland Hischier, Marco Pelin, Fabio Candotto Carniel, Mauro Tretiach, Fabrizia Cesca, Fabio Benfenati, Denis Scaini, Laura Ballerini, Kostas Kostarelos, Maurizio Prato, Alberto Bianco

ACS Nano· Volume 12· Issue 11

Abstract

Graphene and its derivatives are heralded as "miracle" materials with manifold applications in different sectors of society from electronics to energy storage to medicine. The increasing exploitation of graphene-based materials (GBMs) necessitates a comprehensive evaluation of the potential impact of these materials on human health and the environment. Here, we discuss synthesis and characterization of GBMs as well as human and environmental hazard assessment of GBMs using in vitro and in vivo model systems with the aim to understand the properties that underlie the biological effects of these materials; not all GBMs are alike, and it is essential that we disentangle the structure-activity relationships for this class of materials.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Graphene and Nanomaterials Applications · Nanoparticles: synthesis and applications · Microplastics and Plastic Pollution

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Nanosafety & Nanomedicine Laboratory, Institute of Environmental Medicine, Karolinska Institutet, 17777 Stockholm, Sweden

Nanomedicine Laboratory, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom

Faculty of Chemical Science and Technology, University of Castilla-La Mancha, 13071 Ciudad Real, Spain

CNRS, Université Paul Sabatier, 31062 Toulouse, France

National Research Centre for the Working Environment, 2100 Copenhagen, Denmark

University of Strasbourg, CNRS, Immunology, Immunopathology and Therapeutic Chemistry, 67000 Strasbourg, France

Department of Chemistry and Pharmacy University of Sassari, Sassari 7100, Italy

Istituto di Ricerca Pediatrica, Fondazione Città della Speranza, 35129 Padova, Italy

Swiss Federal Laboratories for Materials Science and Technology (EMPA), 9014 St. Gallen, Switzerland

Department of Life Sciences, University of Trieste, 34127 Trieste, Italy

Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, 16132 Genova, Italy

Scuola Internazionale Superiore di Studi Avanzati (SISSA), 34136 Trieste, Italy

Department of Chemical and Pharmaceutical Sciences, University of Trieste, 34127 Trieste, Italy

Carbon Nanobiotechnology Laboratory, CIC BiomaGUNE, 20009 San Sebastian, Spain

Basque Foundation for Science, Ikerbasque, 48013 Bilbao, Spain

Funding

Agence Nationale de la Recherche · FP7 Nanosciences, Nanotechnologies, Materials and new Production Technologies · Centre International de Recherche aux Fronti?res de la Chimie · H2020 Future and Emerging Technologies · Stiftelsen f?r Milj?strategisk Forskning

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