journal article·2025-01-06

Combating Cellular Aging: Frontiers in Biomaterials and Therapies

Senrui Liu, Junyu Mou, Chen Zhao, Chengcheng Du, Jiacheng Liu, Wei Bao, Haozhuo Xiao, Wei Huang, Junyi Liao, Yiting Lei

ACS Materials Letters· Volume 7· Issue 1
Publisher page

Abstract

With the continuous increase in average life expectancy, population aging has become a significant health issue in the 21st century. The rising prevalence of age-related diseases has brought tremendous pressure on social medical systems and the economy. Against this backdrop, research on anticellular aging has become a hot spot in the field of biomedicine, and biomaterials are showing new trends and potential in this area. Compared to drugs and other traditional anti-aging strategies, biomaterials can be personalized to target the aging characteristics of different tissues, serving as drug delivery carriers to enhance targeting, and can directly influence the cellular aging process by modulating the cellular microenvironment. Furthermore, biomaterials offer innovative approaches to diagnosing age-related diseases and building sophisticated models, which enhance our understanding of the biology behind cellular aging and speed up the advancement of novel anti-aging treatments. This review synthesizes the latest advancements in biomaterial research for combating cellular aging, exploring future prospects and potential challenges.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Graphene and Nanomaterials Applications · Advanced Nanomaterials in Catalysis · Extracellular vesicles in disease

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Orthopaedic Surgery

The First Affiliated Hospital of Chongqing Medical University

Chongqing Municipal Health Commission Key Laboratory of Musculoskeletal Regeneration and Translational Medicine

Orthopaedic Research Laboratory of Chongqing Medical University

Department of Pulmonary and Critical Care Medicine

Department of Orthopedics

Affiliated Banan Hospital of Chongqing Medical University

Department of Biomedical Engineering

The Chinese University of Hong Kong

Funding

China Postdoctoral Science Foundation · National Natural Science Foundation of China · Chongqing Medical Youth Top-notch Talent Program · Hong Kong Scholars Program

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