journal article·2022-01-03

Polymeric Matrix-Based Nanoplatforms toward Tumor Therapy and Diagnosis

Houjuan Zhu, Xian Jun Loh, Enyi Ye, Zibiao Li

ACS Materials Letters· Volume 4· Issue 1
Publisher page

Abstract

Flexible polymeric matrixes containing microneedles (MNs), hydrogels, and microcapsules/microspheres have received considerable attention and hold great promise for biomedical applications as delivery systems owing to their superior biocompatibility and biodegradation, excellent patient compliance, and high loading capability. The integration of nanomaterial systems endows polymeric patches with some optimized properties including improved therapeutic efficacy and lowered systemic toxicity, facilitating on-demand and controllable drug delivery, thus extremely expanding their bioapplication. This review briefly summarizes the recent progress of flexible polymeric patches integrated with nanomaterial systems as a delivery approach for tumor therapeutics. In addition, the current challenges, limitations, and future prospects of such therapeutic devices in biomedicine are also discussed.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Advancements in Transdermal Drug Delivery · Nanoparticle-Based Drug Delivery · Advanced Drug Delivery Systems

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Institute of Materials Research and Engineering, A*STAR (Agency for Science, Technology and Research), Singapore 138634, Singapore

Funding

National Environment Agency - Singapore · Agency for Science, Technology and Research

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