journal article·2024-05-06

Preparation and Properties of Self-Assembling Polypeptide Hydrogels and Their Application in Biomedicine

Pengbao Shi, Xiangqiong He, Hailin Cong, Bing Yu, Youqing Shen

ACS Materials Letters· Volume 6· Issue 5
Publisher page

Abstract

Hydrogels are widely used in the field of biomedicine due to their high water content and strong drug loading capacity. Different types and quantities of amino acids are combined to form a wide variety of peptides. At the same time, the self-assembled peptide hydrogel is formed from the peptide into nanofibers, and the nanofibers are further wound to form a three-dimensional structure of the hydrogel. This special structure and the composition of the peptide give the hydrogel special characteristics and properties. Polypeptide-based self-assembled hydrogels have a variety of applications in the biomedical field. Therefore, it is of far-reaching significance to deeply understand polypeptide-based self-assembled hydrogels and explore their applications. This paper introduces the structure, preparation, properties, and biological applications of self-assembling peptide hydrogels. At the same time, the future development of peptide self-assembled gels is prospected.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Supramolecular Self-Assembly in Materials · Advanced biosensing and bioanalysis techniques · Chemical Synthesis and Analysis

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao 266071, P. R. China

State Key Laboratory of Bio-Fibers and Eco-Textiles, Qingdao University, Qingdao 266071, P. R. China

School of Materials Science and Engineering, Shandong University of Technology, Zibo 255000, P. R. China

Key Laboratory of Biomass Chemical Engineering of Ministry of Education, Center for Bionanoengineering, and Department of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, P. R. China

Funding

Government of Shandong Province · National Natural Science Foundation of China · Natural Science Foundation of Shandong Province · Qingdao City · State Key Laboratory of Bio Fibers and Eco Textiles, Qingdao University

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