journal article·2021-01-01Open access

An investigation on the degradation behaviors of Mg wires/PLA composite for bone fixation implants: influence of wire content and load mode

Xuan Li, Yu Cong, Jisheng Sui, Xiaolong Li

Abstract

Abstract Poly-lactic acid based biocomposite strengthened with magnesium alloy wires (Mg wires/PLA composite) is prepared for bone fixation implantation. The influence of wire content and load mode on the degradation performances of the composite and its components is studied. The result suggests the degradation of Mg wires could slow down the pH decrease originated from the degradation of PLA, while a relatively high wire content contributes to descend the degradation rate of Mg wire in the composite. Dynamic load significantly promotes the mechanical loss of the specimens. After 30 days immersion, the S b retention is about 65%, 52% and 55%, respectively for pure PLA, the composite at 10 vol% and 20 vol% under dynamic load, comparing to 75%, 70% and 72% under no load. Moreover, dynamic load could further mitigate the degradation of Mg wires by increasing convective transport of acidic products out of the composite.
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Research context

OpenAlex topics: Magnesium Alloys: Properties and Applications · Orthopaedic implants and arthroplasty · Bone Tissue Engineering Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Materials Science and Engineering , Nanjing Institute of Technology , Nanjing , , China ; Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology , Nanjing Institute of Technology , Nanjing , , China

Department of Orthopedics, Jinling Hospital, School of medicine , Nanjing University , Nanjing , , China

Department of Orthopedics , Nanjing First Hospital of Nanjing Medical University , Nanjing , China

Department of Orthopedics , The affiliated Wujin Hospital of Jiangsu University , Changzhou , China

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