Infection-resistant alloys for implants
Bibliographic record
Abstract
No abstract is available for this record. The assistant can identify its topic from the title, but cannot infer the study’s results.
Source: Not provided · Quality: missing
Research context
OpenAlex topics: Orthopaedic implants and arthroplasty · Titanium Alloys Microstructure and Properties · Orthopedic Infections and Treatments
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (100+)
Show source-provided references
1. Improving biocompatibility for next generation of metallic implants10.1016/j.pmatsci.2022.101053 ↗
2. Metal additive manufacturing for load-bearing implants10.1007/s41745-021-00281-x ↗
3. Biomedical applications of titanium alloys: a comprehensive review10.3390/ma17010114 ↗
4. J. D. Avila, S. Bose, A. Bandyopadhyay, Additive manufacturing of titanium and titanium alloys for biomedical applications, Editor(s): Francis H. Froes, Ma Qian, In Woodhead Publishing Series in Biomaterials, Titanium in Medical and Dental Applications, Woodhead Publishing, 2018, Pages 325-343, ISBN 9780128124567, https://doi.org/10.1016/B978-0-12-812456-7.00015-9.10.1016/B978-0-12-812456-7.00015-9 ↗
5. Hip implant modular junction: The role of CoCrMo alloy microstructure on fretting-corrosion10.1016/j.jmbbm.2022.105402 ↗
6. Bandyopadhyay A, Orozco CL, Upadhayay L, Dash A. Hydroxyapatite-reinforced, infection-resistant CoCrMo-3Cu for load-bearing implants. ACS Appl Mater Interfaces, p. acsami.5c08994, Jul. 2025, doi: 10.1021/acsami.5c08994.10.1021/acsami.5c08994 ↗
7. Mid-term to long-term outcome and risk factors for failure of 158 hips with two-stage revision for periprosthetic hip joint infection10.5194/jbji-10-15-2025 ↗
8. Incidence, microbiological studies, and factors associated with prosthetic joint infection after total knee arthroplasty10.1001/jamanetworkopen.2023.40457 ↗
9. Factors related to surgical site infection in spinal instrumentation surgery: a retrospective study in Japan10.31616/asj.2024.0274 ↗
10. Prevalence, incidence, systemic, behavioral, and patient-related risk factors and indicators for peri-implant diseases: An AO/AAP systematic review and meta-analysis10.1002/JPER.24-0154 ↗
11. Zimmerli W, Trampuz A, Ochsner PE. Prosthetic-Joint Infections. New Engl J Med, 351(16), pp. 1645–1654, Oct. 2004, doi: 10.1056/NEJMra040181.10.1056/NEJMra040181 ↗
12. Martínez-Pastor., et al. Acute infection in total knee arthroplasty: diagnosis and treatment. The open orthopaedics journal. 2013 Jun 14;7:197. doi: 10.2174/1874325001307010197.10.2174/1874325001307010197 ↗
13. Peri-implant mucositis and peri-implantitis: key features and differences10.1038/s41415-024-7402-z ↗
14. Implant infections: adhesion, biofilm formation and immune evasion10.1038/s41579-018-0019-y ↗
15. Prosthetic joint infection10.1128/CMR.00111-13 ↗
16. Kurtz SM, Lau E, Watson H, Schmier JK, Parvizi J. Economic burden of periprosthetic joint infection in the United States. J Arthroplasty, 2(8), Supplement, pp. 61-65.e1, Sep. 2012, doi: 10.1016/j.arth.2012.02.022.10.1016/j.arth.2012.02.022 ↗
17. The rate and management of prosthetic joint infection in the low-income setting: a cross-sectional study10.1097/MS9.0000000000000430 ↗
18. Additively manufactured Ti–Ta–Cu alloys for the next-generation load-bearing implants10.1088/2631-7990/ad07e7 ↗
19. The health-economic burden of hip and knee periprosthetic joint infections in Europe10.1302/2633-1462.63.BJO-2024-0225.R1 ↗
20. Bio-inspired nanostructured Ti-6Al-4V alloy: the role of two alkaline etchants and the hydrothermal processing duration on antibacterial activity10.3390/nano12071140 ↗
21. Implications of biofilm formation on urological devices10.1063/1.2998011 ↗
22. Microbial biofilm: a review on formation, infection, antibiotic resistance, control measures, and innovative treatment10.3390/microorganisms11061614 ↗
23. Prosthesis infections after orthopedic joint replacement: the possible role of bacterial biofilms
24. Infections associated with orthopedic implants10.1097/01.qco.0000235161.85925.e8 ↗
25. Veerachamy S, Yarlagadda T, Manivasagam G, Yarlagadda P. Bacterial adherence and biofilm formation on medical implants: a review. Proc Inst Mech Eng. Part H, J Eng Med, 228 (2014) 1083–1099, Oct., doi: 10.1177/0954411914556137.10.1177/0954411914556137 ↗
26. Pathogenesis and prevention of biomaterial centered infections10.1023/A:1016175502756 ↗
27. Biomaterial-centered infection: microbial adhesion versus tissue integration10.1126/science.3629258 ↗
28. Costerton JW. The biofilm primer. in Springer series on biofilms, 1. Berlin; Springer, 2007.10.1007/b136878 ↗
29. The biofilm life cycle: expanding the conceptual model of biofilm formation10.1038/s41579-022-00767-0 ↗
30. Drug treatments for prosthetic joint infections in the era of multidrug resistance10.1080/14656566.2016.1176142 ↗
31. Clinical outcome and microbiological findings using antibiotic-loaded spacers in two-stage revision of prosthetic joint infections10.1016/j.jinf.2011.04.014 ↗
32. Decreased Staphylococcus epidermis adhesion and increased osteoblast functionality on antibiotic-loaded titania nanotubes10.1016/j.biomaterials.2007.07.037 ↗
33. What is the rate of antimicrobial resistance of a prosthetic joint infection in a major orthopaedic centre?10.3390/antibiotics13040306 ↗
34. Periprosthetic joint infection: a multifaceted burden undermining arthroplasty success10.52965/001c.138205 ↗
35. Two-stage revision of septic knee prosthesis with articulating knee spacers yields better infection eradication rate than one-stage or two-stage revision with static spacers10.1007/s00167-012-1885-x ↗
36. The epidemiology of revision total knee arthroplasty in the United States10.1007/s11999-009-0945-0 ↗
37. Surface modification of biomaterials and biomedical devices using additive manufacturing10.1016/j.actbio.2017.11.003 ↗
38. Antimicrobial nanomaterials and coatings: current mechanisms and future perspectives to control the spread of viruses including SARS-CoV-210.1021/acsnano.0c05937 ↗
39. Antibacterial and biological characteristics of plasma sprayed silver and strontium doped hydroxyapatite coatings10.1016/j.actbio.2012.04.004 ↗
40. Antimicrobial treatment of polymeric medical devices by silver nanomaterials and related technology10.3390/ijms18020419 ↗
41. Constructing multilayer silk protein/nanosilver biofunctionalized hierarchically structured 3D printed Ti6Al4 V scaffold for repair of infective bone defects10.1021/acsbiomaterials.8b00857 ↗
42. Zn/Ag micro-galvanic couples formed on titanium and osseointegration effects in the presence of S.aureus10.1016/j.biomaterials.2015.06.040 ↗
43. Advancements in antimicrobial surface coatings using metal/metaloxide nanoparticles, antibiotics, and phytochemicals10.3390/nano15131023 ↗
44. Efflux pump inhibitors: new updates10.1007/s43440-020-00160-9 ↗
45. Antibacterial layer-by-layer coatings for medical implants10.3390/pharmaceutics13010016 ↗
46. Fluoride modification effects on osteoblast behavior and bone formation at TiO2 grit-blasted c.p. titanium endosseous implants10.1016/j.biomaterials.2005.07.009 ↗
47. Quorum-sensing regulation of antimicrobial resistance in bacteria10.3390/microorganisms8030425 ↗
48. Controlled release of vancomycin from thin sol–gel films on titanium alloy fracture plate material10.1016/j.biomaterials.2006.11.035 ↗
49. Combating medical device fouling10.1016/j.tibtech.2013.12.004 ↗
50. “Anti-Adhesive Coatings,” in Green Adhesives
51. Anti‐adhesive properties of fish tropomyosins10.1111/j.1365-2672.2007.03718.x ↗
52. Recent advances in antibacterial coatings to combat orthopedic implant-associated infections10.3390/molecules29051172 ↗
53. Recent advances in metal-based antimicrobial coatings10.1016/j.cis.2025.103590 ↗
54. External stimuli-responsive strategies for surface modification of orthopedic implants: killing bacteria and enhancing osteogenesis10.1021/acsami.3c19149 ↗
55. Copper reduction and contact killing of bacteria by iron surfaces10.1128/AEM.01725-15 ↗
56. Key topographic parameters driving surface adhesion of porphyromonas gingivalis10.1038/s41598-023-42387-5 ↗
57. Trivedi RR, et al. Mechanical genomic studies reveal the role of d-alanine metabolism in pseudomonas aeruginosa cell stiffness. mBio, 9(5), p. 10.1128/mbio.01340-18, Sep. 2018, doi: 10.1128/mbio.01340-18.10.1128/mBio.01340-18 ↗
58. Natural bactericidal surfaces: mechanical rupture of pseudomonas aeruginosa cells by cicada wings10.1002/smll.201200528 ↗
59. Smart stimuli-responsive strategies for titanium implant functionalization in bone regeneration and therapeutics10.1039/D3MH01260C ↗
60. Recent advances in stimuli-responsive antibacterial coatings: bacteria-killing and releasing mechanism, design strategies, and potential applications
61. Cell membrane-inspired polymeric vesicles for combined photothermal and photodynamic prostate cancer therapy10.1021/acsami.0c11636 ↗
62. Which parameters affect biofilm removal with acoustic cavitation? a review10.1016/j.ultrasmedbio.2019.01.002 ↗
63. Kujundzic E, Cristina Fonseca A, Evans EA, Peterson M, Greenberg AR, Hernandez M. Ultrasonic monitoring of earlystage biofilm growth on polymeric surfaces. J Microbiol Methods, 68(3), pp. 458–467, Mar. 2007, doi: 10.1016/j.mimet.2006.10.005.10.1016/j.mimet.2006.10.005 ↗
64. Mechanisms of the bactericidal activity of low amperage electric current (DC)10.1093/jac/39.6.687 ↗
65. Electrically polarized biomaterials10.1002/adma.201505403 ↗
66. Determination of bacterial surface charge density via saturation of adsorbed ions10.1016/j.bpj.2021.04.018 ↗
67. Conducting photopolymers on orthopeadic implants having a switch of priority between promoting osteogenic and antibacterial activity10.1039/C8MH00285A ↗
68. Magnetic targeting of surface-modified superparamagnetic iron oxide nanoparticles yields antibacterial efficacy against biofilms of gentamicin-resistant staphylococci10.1016/j.actbio.2012.03.002 ↗
69. NIR-induced improvement of catalytic activity and antibacterial performance over AuAg nanorods in Rambutan-like Fe3O4@AgAu@PDA magnetic nanospheres10.1016/j.jhazmat.2022.130616 ↗
70. Magnetic hyperthermia–synergistic H2O2 self-sufficient catalytic suppression of osteosarcoma with enhanced bone-regeneration bioactivity by 3D-printing composite scaffolds10.1002/adfm.201907071 ↗
71. Revision total knee arthroplasty infection: incidence and predictors10.1007/s11999-010-1308-6 ↗
72. Habboush Y, Guzman N. Antibiotic resistance,” in StatPearls, Treasure Island (FL): StatPearls Publishing, 2025. Accessed: Dec. 28, 2025. [Online]. Available: http://www.ncbi.nlm.nih.gov/books/NBK513277/.
73. Biofilms: survival mechanisms of clinically relevant microorganisms10.1128/CMR.15.2.167-193.2002 ↗
74. Teichoic acids and related cell-wall glycopolymers in gram-positive physiology and host interactions10.1038/nrmicro1861 ↗
75. The bacterial cell envelope10.1101/cshperspect.a000414 ↗
76. Strategies and applications of antibacterial surface-modified biomaterials
77. Corrosion of metallic biomaterials: a review10.3390/ma12030407 ↗
78. Influence of the microstructure and silver content on degradation, cytocompatibility, and antibacterial properties of magnesium-silver alloys in vitro10.1155/2017/8091265 ↗
79. Detecting excess biofilm thickness in microbial electrolysis cells by real‐time in‐situ biofilm monitoring10.1002/bit.29017 ↗
80. Theoretical aspects of antibiotic diffusion into microbial biofilms10.1128/AAC.40.11.2517 ↗
81. Antibacterial effect of copper-bearing titanium alloy (Ti-Cu) against Streptococcus mutans and Porphyromonas gingivalis10.1038/srep29985 ↗
82. Antibacterial metals —a viable solution for bacterial attachment and microbiologically influenced corrosion—10.2320/matertrans.46.1636 ↗
83. Evaluation of antibacterial ability of some pure metals
84. A review of the clinical implications of anti-infective biomaterials and infection-resistant surfaces10.1016/j.biomaterials.2013.07.048 ↗
85. Recent advances in research on antibacterial metals and alloys as implant materials10.3389/fcimb.2021.693939 ↗
86. Toxicity mechanism of Cu2+ ion individually and in combination with Zn2+ ion in characterizing the molecular changes of Staphylococcus aureus studied using FTIR coupled with chemometric analysis10.1007/s10867-020-09560-7 ↗
87. I. T, “Mechanism of Antibacterial Activities of Cu (Ⅱ) ions against staphylococcus aureus and escherichia coli on the ground of results obtained from dilution medium method,” VIJ, vol. 1, no. 3, 2017, doi: 10.23880/VIJ-16000117.10.23880/VIJ-16000117 ↗
88. Survival and growth in the presence of elevated copper: transcriptional profiling of copper-stressed Pseudomonas aeruginosa10.1128/JB.00837-06 ↗
89. Vila Domínguez A, Ayerbe Algaba R, Miró Canturri A, Rodríguez Villodres Á, Smani Y. Antibacterial activity of colloidal silver against gram-negative and gram-positive bacteria. Antibiotics (Basel), 9(1), p. 36, Jan. 2020, doi: 10.3390/antibiotics9010036.10.3390/antibiotics9010036 ↗
90. Morones-Ramirez JR, Winkler JA, Spina CS, Collins JJ. Silver enhances antibiotic activity against gram-negative bacteria. Sci Transl Med, 5(190), p. 190ra81, Jun. 2013, doi: 10.1126/scitranslmed.3006276.10.1126/scitranslmed.3006276 ↗
91. Deumić S, El Sayed A, Hsino M, Glamočak A, Crnčević N, Avdić M. Investigating the effect of iron salts on E. coli and E. faecalis biofilm formation in water distribution pipelines. Water, 17(6), p. 886, Jan. 2025, doi: 10.3390/w17060886.10.3390/w17060886 ↗
92. Where does the toxicity of metal oxide nanoparticles come from: the nanoparticles, the ions, or a combination of both?10.1016/j.jhazmat.2016.01.066 ↗
93. Antimicrobial effect of gallium nitrate against bacteria encountered in burn wound infections10.1039/C7RA10265H ↗
94. Antibacterial biodegradable Mg-Ag alloys10.22203/eCM.v025a20 ↗
95. Cytotoxicity evaluation of 43 metal salts using murine fibroblasts and osteoblastic cells10.1002/(SICI)1097-4636(199802)39:2<331::AID-JBM22>3.0.CO;2-E ↗
96. A novel antibacterial titania coating: Metal ion toxicity and in vitro surface colonization10.1007/s10856-005-4422-3 ↗
97. Antimicrobial activity of gallium compounds on ESKAPE pathogens10.3389/fcimb.2018.00316 ↗
98. Metallurgical gallium additions to titanium alloys demonstrate a strong time-increasing antibacterial activity without any cellular toxicity10.1021/acsbiomaterials.9b00147 ↗
99. Synergistic antibacterial effects of exopolysaccharides/nickel-nanoparticles composites against multidrug-resistant bacteria10.1038/s41598-023-48821-y ↗
100. Nickel nanoparticles: applications and antimicrobial role against methicillin-resistant staphylococcus aureus infections10.3390/antibiotics11091208 ↗