"STINGLESS BEE HONEY INCORPORATED CELLULOSE HYDROGEL/POLY(LACTIC-CO-GLYCOLIC ACID) PATCH AS AN ALTERNATIVE TREATMENT FOR APHTHOUS STOMATITIS
Source abstract
Abstract
Aphthous stomatitis is a disease that often reappears, causing irritation and pain. Common topical medications to treat aphthous stomatitis are fast-dissolving synthetic drugs, sometimes with limited therapeutic effectiveness. In this study, a patch, composed of a stingless bee honey incorporated cellulose hydrogel layer and a poly(lactic-co-glycolic acid) (PLGA) layer, was fabricated as an alternative treatment for aphthous stomatitis. The composition of the honey patches was verified by the presence of a distinct physical structure, considerable wettability records and lower degradation percentages on the layers containing higher PLGA concentrations. The honey patches were capable to retard Eschericia coli in the early hours (0.5-2 hours) and Staphylococcus aureus in the late hours (2-4 hours) of application, with tolerable cell viability and cell closure. The therapeutic values of the honey patches in retarding bacterial growth and inducing cell closure recommend the developed patches to be used in aphthous stomatitis treatment.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Bee Products Chemical Analysis · Nail Diseases and Treatments · Plant Surface Properties and Treatments
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
School of Biomedical Engineering and Health Sciences, Faculty of Engineering, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia
Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, Taiwan
Academy of Islamic Civilization, Faculty of Social Science and Humanities, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia
References (39)
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