DataVXACS Applied Polymer MaterialsPaper
journal article·2024-11-22

A Two-Stage Functional Nanomaterial Utilized for Ethanolamine Scavenging and Formaldehyde Detection via the AILE Mechanism

Shuo Zhu, Ruiqi Cui, Sicong Liu, Weihao Chen, Shouhui Huang, Genbao Zhu, Meng Liu, Jutao Sun, Lili Li, Xinlong Pang

ACS Applied Polymer Materials· Volume 6· Issue 22
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Source abstract

Abstract

Based on the principle of intermolecular interactions of the aggregation-induced locally excited emission (AILE) luminescence mechanism, two-stage functional conjugated polymers (CPs) capable of scavenging ethanolamine (ETA) and nanoprobes with detecting formaldehyde (FA) were designed and developed. The two-stage functional PFOP-NEt3(+)-based nanomaterial is simple to synthesize, easy to use, versatile, atom-economical, photostability, and biocompatible. In the first stage, conjugated polymers can process and stabilize the water pollutant ethanolamine. In the second stage, the nanoparticles formed by self-assembling conjugated polymers with ethanolamine can produce specific and sensitive responses to formaldehyde. They can detect formaldehyde in normal and cancer cells. This two-stage functional material, which has a high atom economy, is expected to be a specific detection probe for formaldehyde in vivo and ex vivo and can remove ethanolamine from aqueous environments and cells.
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Research context

PolymersNanomaterialsBiomaterials

OpenAlex topics: Electrochemical sensors and biosensors · Advanced Chemical Sensor Technologies · Gas Sensing Nanomaterials and Sensors

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Key Laboratory of Rubber-Plastics, Ministry of Education/Shandong Provincial Key Laboratory of Rubber and Plastics, Qingdao University of Science and Technology, Qingdao 266042, China

Shenzhen Key Laboratory of Cardiovascular Disease, Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen 518038, China

The State Key Laboratory of Chemical Oncogenomics, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, People’s Republic of China

School of Pharmacy, Shenzhen University Medical School, Shenzhen University, Shenzhen 518055, China

General Clinical Research Center, Anhui Wanbei Coal-Electricity Group General Hospital, Suzhou 234000, China

Funding

Suzhou Municipal Science and Technology Bureau · Shenzhen Municipal Fundamental Research Program · Basic and Applied Basic Research Foundation of Guangdong Province · Shenzhen High-level Hospital Construction Fund · Anhui Provincial Health Commission · Shenzhen Key Laboratory of Cardiovascular Disease, Fuwai Shenzhen Hospital, Chinese Academy of Medical Sciences

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