DataVXACS Applied Polymer MaterialsPaper
journal article·2023-11-10

Facile Syntheses of a Poly-2-phenylbenzobisthiazole-Based Theranostic Nanoplatform

Lei Xin, Lei Wang, Qian Wang, Jian Meng, Jinfang Gao, Ruiping Zhang

ACS Applied Polymer Materials· Volume 5· Issue 11
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Source abstract

Abstract

Photothermal therapy (PTT) is a therapeutic method emerging in recent years, and the photothermal conversion performance of the photothermal agent directly determines the effect of PTT. Poly-2-phenylbenzobisthiazole (PB) is a type of conjugated polymer with a simple synthesis method. It has good biocompatibility and degradability as well as excellent photothermal properties. However, the poor hydrophilicity of PB limits its application in biomaterials. In this work, a reversed-phase precipitation self-assembly method was used to prepare and obtain well-dispersed PB-based nanoparticles. PB and ferric chloride were first dissolved in N -methylpyrrolidone, after which the mixed solution was added dropwise to an aqueous solution of polyphenol and hyaluronic acids. The polyphenol–metal self-assembly network was complexed with PB molecular chains. The water-soluble nanoparticles PFGH prepared exhibited good photothermal properties and had great potential in the field of PTT.
Source: openalex_inverted_index · Quality: baseline

Research context

PolymersNanomaterialsBiomaterials

OpenAlex topics: Nanoplatforms for cancer theranostics · Nanoparticle-Based Drug Delivery · Dendrimers and Hyperbranched Polymers

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Shanxi Province Cancer Hospital, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan 030013, China

The Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Taiyuan 030032, China

Shanxi Academy of Medical Sciences, Shanxi Medical University, Taiyuan 030001, China

Shanxi Provincial People’s Hospital, The Fifth Hospital of Shanxi Medical University, Taiyuan 030012, China

Funding

Natural Science Foundation of Shanxi Province · Shaanxi Provincial Health Commission · Program for the Scientific Activities of Selected Returned Overseas Professionals in Shaanxi Province · National Natural Science Foundation of China · Shanxi Scholarship Council of China · Key Laboratory of Nano-imaging and Drug-loaded Preparation of Shanxi Province

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