Preparation and Properties of Semi-Interpenetrating Silk Fibroin Protein Hydrogels with Integrated Strength and Toughness
Source abstract
Abstract
Two series of semi-interpenetrating network hydrogels (P(AAN-co-AAM)-SF and P(AA-co-AAM)-SF) were constructed through one-step blending of silk fibroin with sodium acrylate or acrylic acid followed by ultraviolet (UV)-initiated free-radical copolymerization. The resulting silk fibroin composite hydrogels exhibited excellent mechanical properties due to the semi-interpenetrating network hydrogel formed by sodium polyacrylate and silk fibroin. Specifically, the P(AAN-co-AAM)-SF hydrogel showed a high fracture stress of 1.01 MPa, an elongation at break of 2000%, a high compressive strength of 17 MPa, and could be compressed up to 200 cycles without damage. Compared with other silk fibroin hydrogels, this work was in a leading position in terms of mechanical properties and antidrying ability. In addition, silk fibroin-based hydrogels showed no cytotoxicity, certain UV-shielding ability, and were specifically poured into pig tracheal sections, indicating the potential for future use as biological materials.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Silk-based biomaterials and applications · Electrospun Nanofibers in Biomedical Applications · Biochemical and Structural Characterization
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Guangdong Provincial Key Laboratory of Agro-Animal Genomics, National Engineering Research Center for Breeding Swine Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China
Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, 483 Wushan Road, Guangzhou 510642, China
Joint Laboratory of Guangdong Province and Hong Kong Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural Universtiy, Guangzhou 510641, China
Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China
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