Chiral Covalent Organic Frameworks as Promising Materials for Racemate Resolution
Source abstract
Abstract
Enantiomeric excess and purity play pivotal roles across various fields, foremost among them the pharmaceutical industry. Chiral resolution is a crucial technique, enabling the analysis of enantiomeric excess and the procurement of purified enantiomers. Despite their widespread utilization, chiral materials still encounter numerous challenges. Recently, covalent organic frameworks (COFs), as emerging porous organic materials, stand out as promising platforms for various applications due to their high porosity, ordered crystallinity, and exceptional thermal and chemical stability. In particular, the chiral COFs (CCOFs) have emerged as promising candidates for racemate resolution. However, systematic reviews on chiral resolution utilizing CCOFs are scant, likely due to their nascent application. This review delves into the synthesis of CCOFs, summarizing three primary methods: direct synthesis, postsynthesis, and chiral induction. Additionally, it offers an insightful exploration of CCOFs’ applications in racemate resolution. Lastly, this review highlights the current challenges and future prospects for their further development and utilization.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Covalent Organic Framework Applications · Metal-Organic Frameworks: Synthesis and Applications · Surface Chemistry and Catalysis
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
School of Environmental Science and Engineering, Shandong Key Laboratory of Environmental Processes and Health, Shandong University, Qingdao 266237, People’s Republic of China
Shenzhen Research Institute, Shandong University, Virtual University Park, Nanshan District, Shenzhen 518057, People’s Republic of China
MacDiarmid Institute for Advanced Materials and Nanotechnology, School of Natural Sciences, Massey University, Palmerston North 4442, New Zealand
Paihau-Robinson Research Institute, Victoria University of Wellington, Wellington 6140, New Zealand
The MacDiarmid Institute for Advanced Materials and Nanotechnology, Wellington 6140, New Zealand
NJTECH University Suzhou Future Membrane Technology Innovation Center, Su Zhou, 215519, People’s Republic of China
Funding
Science and Technology Foundation of Shenzhen City · National Natural Science Foundation of China · Jiangsu Future Membrane Technology Innovation Center
References (81)
Show source-provided references
1. 10.1126/science.212.4499.114510.1126/science.212.4499.1145 ↗
2. 10.1039/D1CS01179K10.1039/D1CS01179K ↗
3. 10.1002/chir.2345310.1002/chir.23453 ↗
4. 10.1016/j.trac.2017.05.01310.1016/j.trac.2017.05.013 ↗
5. 10.1021/acs.chemmater.3c0285910.1021/acs.chemmater.3c02859 ↗
6. 10.1021/acs.jafc.3c0256410.1021/acs.jafc.3c02564 ↗
7. 10.1038/s41557-019-0380-010.1038/s41557-019-0380-0 ↗
8. 10.1016/j.seppur.2022.12103410.1016/j.seppur.2022.121034 ↗
9. 10.1016/j.chroma.2021.46187810.1016/j.chroma.2021.461878 ↗
10. 10.1016/j.ccr.2023.21539210.1016/j.ccr.2023.215392 ↗
11. 10.1002/chir.2349210.1002/chir.23492 ↗
12. 10.1002/chir.2330310.1002/chir.23303 ↗
13. 10.1021/acs.nanolett.3c0000410.1021/acs.nanolett.3c00004 ↗
14. 10.1016/j.memsci.2022.12110710.1016/j.memsci.2022.121107 ↗
15. 10.1016/j.memlet.2022.10003110.1016/j.memlet.2022.100031 ↗
16. 10.1016/j.trac.2014.10.00910.1016/j.trac.2014.10.009 ↗
17. 10.3390/molecules2611338010.3390/molecules26113380 ↗
18. 10.1016/j.cej.2022.13949910.1016/j.cej.2022.139499 ↗
19. 10.2533/chimia.2017.43010.2533/chimia.2017.430 ↗
20. 10.3390/separations303002710.3390/separations3030027 ↗
21. 10.1016/j.isci.2020.10132610.1016/j.isci.2020.101326 ↗
22. 10.1039/C9CS00827F10.1039/C9CS00827F ↗
23. 10.1002/anie.20150493410.1002/anie.201504934 ↗
24. 10.1021/acs.analchem.1c0362610.1021/acs.analchem.1c03626 ↗
25. 10.1016/j.chroma.2022.46334110.1016/j.chroma.2022.463341 ↗
26. 10.1039/C2CS35072F10.1039/C2CS35072F ↗
27. 10.1126/science.aal158510.1126/science.aal1585 ↗
28. 10.1038/natrevmats.2016.6810.1038/natrevmats.2016.68 ↗
29. 10.1016/j.cclet.2017.03.02610.1016/j.cclet.2017.03.026 ↗
30. 10.1038/s41467-019-10504-610.1038/s41467-019-10504-6 ↗
31. 10.3389/fenrg.2019.0007710.3389/fenrg.2019.00077 ↗
32. 10.1021/jacs.9b0807910.1021/jacs.9b08079 ↗
33. 10.1007/s11426-017-9070-110.1007/s11426-017-9070-1 ↗
34. 10.3390/membranes1203030710.3390/membranes12030307 ↗
35. 10.1016/j.enchem.2020.10003510.1016/j.enchem.2020.100035 ↗
36. 10.1126/science.112041110.1126/science.1120411 ↗
37. 10.1002/app.5151010.1002/app.51510 ↗
38. 10.1002/asia.20200087210.1002/asia.202000872 ↗
39. 10.1016/j.diamond.2017.09.00510.1016/j.diamond.2017.09.005 ↗
40. 10.1002/anie.20200737210.1002/anie.202007372 ↗
41. 10.1039/D0CS00620C10.1039/D0CS00620C ↗
42. 10.1021/jacs.6b0751610.1021/jacs.6b07516 ↗
43. 10.1016/j.saa.2023.12237010.1016/j.saa.2023.122370 ↗
44. 10.1016/j.snb.2021.13125310.1016/j.snb.2021.131253 ↗
45. 10.1016/j.apcatb.2019.11845610.1016/j.apcatb.2019.118456 ↗
46. 10.1002/chir.2322710.1002/chir.23227 ↗
47. 10.1021/jacs.3c0573210.1021/jacs.3c05732 ↗
48. 10.1021/acssuschemeng.8b0588710.1021/acssuschemeng.8b05887 ↗
49. 10.1039/C9QI01103J10.1039/C9QI01103J ↗
50. 10.1021/jacs.6b0771410.1021/jacs.6b07714 ↗
51. 10.1039/D1CS00804H10.1039/D1CS00804H ↗
52. 10.1021/acsami.1c0923810.1021/acsami.1c09238 ↗
53. 10.1039/C3CC48813F10.1039/C3CC48813F ↗
54. 10.1038/s41467-018-03689-910.1038/s41467-018-03689-9 ↗
55. 10.1021/acs.chemrev.0c0124410.1021/acs.chemrev.0c01244 ↗
56. 10.1016/j.jcoa.2023.10009910.1016/j.jcoa.2023.100099 ↗
57. 10.1021/acsami.1c2098910.1021/acsami.1c20989 ↗
58. 10.1021/acs.analchem.8b0484110.1021/acs.analchem.8b04841 ↗
59. 10.1038/ncomms1210410.1038/ncomms12104 ↗
60. 10.1016/j.talanta.2023.12458910.1016/j.talanta.2023.124589 ↗
61. 10.1016/j.chroma.2022.46307010.1016/j.chroma.2022.463070 ↗
62. 10.1021/acsami.9b1672010.1021/acsami.9b16720 ↗
63. 10.1021/acs.chemrev.1c0084610.1021/acs.chemrev.1c00846 ↗
64. 10.1039/D1TA04621G10.1039/D1TA04621G ↗
65. 10.1039/C1CS15135E10.1039/C1CS15135E ↗
66. 10.1016/j.chroma.2022.46315510.1016/j.chroma.2022.463155 ↗
67. 10.1016/j.chroma.2021.46273110.1016/j.chroma.2021.462731 ↗
68. 10.1021/acs.chemmater.2c0314010.1021/acs.chemmater.2c03140 ↗
69. 10.1039/D2NJ06097C10.1039/D2NJ06097C ↗
70. 10.1016/j.trac.2019.11564010.1016/j.trac.2019.115640 ↗
71. 10.1016/j.jpba.2004.03.00810.1016/j.jpba.2004.03.008 ↗
72. 10.1016/j.talanta.2023.12441510.1016/j.talanta.2023.124415 ↗
73. 10.1016/j.chroma.2019.06.01810.1016/j.chroma.2019.06.018 ↗
74. 10.1016/j.chroma.2022.46294310.1016/j.chroma.2022.462943 ↗
75. 10.1016/j.cej.2020.12824710.1016/j.cej.2020.128247 ↗
76. 10.1039/D4CC01608D10.1039/D4CC01608D ↗
77. 10.1021/jacs.9b1000710.1021/jacs.9b10007 ↗
78. 10.1002/anie.20220401210.1002/anie.202204012 ↗
79. 10.1016/j.chroma.2021.46247510.1016/j.chroma.2021.462475 ↗
80. 10.1016/j.seppur.2021.12033610.1016/j.seppur.2021.120336 ↗
81. 10.1016/j.seppur.2023.12440610.1016/j.seppur.2023.124406 ↗