DataVXACS Applied Nano MaterialsPaper
journal article·2026-04-17

Quantum Dot-Amphiphilic Polymer Composite Colloids for Nitric Oxide Sensing

Wonseok Lee, Junhwa Lee, Hyunjung Lee, Dakyeon Lee, Eunjeong Jang, Joonhyuck Park, Sungjee Kim

ACS Applied Nano Materials· Volume 9· Issue 15
Publisher page
Source abstract

Abstract

Nitric oxide (NO) regulates diverse physiological pathways, functioning as an immune mediator, vascular regulator, and neurotransmitter. Sensitive and selective NO readout is important for biomedical research and diagnostics. We report two types of QD-amphiphilic polyethylenimine (amPEI) composite probes that showcase ratiometric detection of NO. The composites coencapsulate large numbers of fluorescent quantum dots (QDs) together with distinct cohosted NO-responsive molecules: the fluorescent dye 1,2-diaminoanthraquinone or the colorimetric ferric tetra-amido macrocyclic ligand [Fe(TAML)] complex. The flexible amPEI scaffold provides hydrophobic pockets that promote efficient gas permeation and probe–analyte interactions. Both types of composite probes exhibit a fast response and high sensitivity, showcasing submicromolar limits of detection. This multicomponent ratiometric design underscores the robustness and reliability for NO sensing, potentially in complex environments.
Source: openalex_inverted_index · Quality: baseline

Research context

PolymersComposites

OpenAlex topics: Carbon and Quantum Dots Applications · Electrochemical sensors and biosensors · Analytical Chemistry and Sensors

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Chemistry, Pohang University of Science and Technology (POSTECH), 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk 37673, Republic of Korea

Department of Bioengineering

University of Illinois Urbana−Champaign

Department of Medical Life Sciences and Department of Medical Sciences (Graduate School), College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea

Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea

School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk 37673, Republic of Korea

Funding

Korea Health Industry Development Institute · National Research Foundation of Korea · Catholic Education Foundation

References (32)

Show source-provided references
1. 10.1039/b716174c10.1039/b716174c ↗
2. 10.1021/acssensors.1c0005110.1021/acssensors.1c00051 ↗
3. 10.1016/j.sintl.2021.10011610.1016/j.sintl.2021.100116 ↗
4. 10.1016/j.snr.2022.10010010.1016/j.snr.2022.100100 ↗
5. 10.1021/acs.chemrev.4c0059210.1021/acs.chemrev.4c00592 ↗
6. 10.1021/acs.chemrev.8b0079710.1021/acs.chemrev.8b00797 ↗
7. 10.1021/acs.chemrev.5b0001810.1021/acs.chemrev.5b00018 ↗
8. 10.1073/pnas.050513610210.1073/pnas.0505136102 ↗
9. 10.1021/ac061791b10.1021/ac061791b ↗
10. 10.1038/nchembio79410.1038/nchembio794 ↗
11. 10.1002/1521-3773(20000616)39:12<2120::AID-ANIE2120>3.0.CO;2-M10.1002/1521-3773(20000616)39:12<2120::AID-ANIE2120>3.0.CO;2-M ↗
12. 10.1021/ic035418n10.1021/ic035418n ↗
13. 10.1039/b207726d10.1039/b207726d ↗
14. 10.1016/j.freeradbiomed.2018.01.02710.1016/j.freeradbiomed.2018.01.027 ↗
15. 10.1002/cbic.20110037110.1002/cbic.201100371 ↗
16. 10.1021/ac001136i10.1021/ac001136i ↗
17. 10.1021/ac980172310.1021/ac9801723 ↗
18. 10.1146/annurev-anchem-060908-15513610.1146/annurev-anchem-060908-155136 ↗
19. 10.1021/acssensors.7b0035610.1021/acssensors.7b00356 ↗
20. 10.1039/C4CC10149A10.1039/C4CC10149A ↗
21. 10.1016/j.matlet.2014.02.07810.1016/j.matlet.2014.02.078 ↗
22. 10.1021/acsbiomaterials.0c0084210.1021/acsbiomaterials.0c00842 ↗
23. 10.1021/ja904824w10.1021/ja904824w ↗
24. 10.1021/acsnano.5b0235710.1021/acsnano.5b02357 ↗
25. 10.1021/acsnano.5c0196510.1021/acsnano.5c01965 ↗
26. 10.1021/cm902516f10.1021/cm902516f ↗
27. 10.1021/ja075047010.1021/ja0750470 ↗
28. 10.1002/anie.20100230710.1002/anie.201002307 ↗
29. 10.1021/ac501315p10.1021/ac501315p ↗
30. 10.1039/c2cc37221e10.1039/c2cc37221e ↗
31. 10.1021/ac970706k10.1021/ac970706k ↗
32. 10.1021/ac981046210.1021/ac9810462 ↗