DataVXACS Applied Nano MaterialsPaper
journal article·2026-01-30

Solvent-Free Mechanochemical Synthesis of Cyclodextrin Nanosponges via Mechanical Milling for Removal of Dinotefuran from Water

Sebastián Salazar Sandoval, Arianne Maine, Freddy Celis, Diego Cortés-Arriagada, Ximena Briones, Rodrigo Araya-Hermosilla, Germán Günther, María de los Ángeles Moreno, Paul Jara, Francisco Melo, Marcelo J. Kogan, Ana Riveros, Nataly Silva

ACS Applied Nano Materials· Volume 9· Issue 4
Publisher page
Source abstract

Abstract

Cyclodextrin-based nanosponges (NSs) have gained attention as sustainable adsorbents for emerging pollutants. However, conventional cyclodextrin cross-linking typically involves toxic solvents and prolonged reaction times, which complicate synthesis and purification. In this work, NSs were synthesized using a solvent-free mechanochemical process via mechanical milling with diphenyl carbonate as a cross-linker. The structural and physicochemical properties of the obtained NSs were characterized using morphological (FE-SEM, TEM, EDS), spectroscopic (FT-IR, Raman, NMR), thermal (TGA, DSC), and crystallographic (XRD) techniques, confirming successful cross-linking. The adsorption performance of the NSs was evaluated using dinotefuran, a model neonicotinoid pollutant. Kinetic and equilibrium studies revealed rapid adsorption within 60 min, with a removal efficiency (RE%) of 98%. The equilibrium data were best fitted by employing the Freundlich and Temkin isotherms, indicating a heterogeneous multilayer adsorption process dominated by supramolecular interactions. Notably, when tested in real river water samples from the Maipo River (Chile), the NSs maintained a high RE% of 75% and demonstrated stable performance over multiple adsorption–desorption cycles, confirming their reusability under environmentally relevant conditions. This sustainable and scalable synthesis approach, coupled with strong performance in both laboratory and natural water matrices, highlights the potential of these NSs as viable materials for water treatment applications.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Adsorption and biosorption for pollutant removal · Layered Double Hydroxides Synthesis and Applications · Boron and Carbon Nanomaterials Research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Departamento de Química Orgánica y Fisicoquímica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile. Dr. Carlos Lorca Tobar 964, Independencia, Región Metropolitana, Casilla 233, Santiago 1025000, Chile

Departamento de Química de los Materiales, Facultad de Química y Biología, Universidad de Santiago de Chile, Soft Matter Research-Technology Center, SMAT-C, Av. B. O’Higgins 3363, Santiago 9170022, Chile

Instituto de Química, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso, Av. Brasil 2950, Valparaíso 9170022, Chile

Instituto Universitario de Investigación y Desarrollo Tecnológico (IDT), Universidad Tecnológica Metropolitana, Ignacio Valdivieso 2409, San Joaquín, Santiago 8940577, Chile

Facultad de Diseño, Universidad del Desarrollo, Ainavillo 456, Concepción 4070001, Chile

Departamento de Química, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425, Ñuñoa, Santiago 7800003, Chile

Departamento de Química Farmacológica y Toxicológica, Facultad de Ciencias Químicas y Farmacéuticas, Dr. Carlos Lorca Tobar 964, Universidad de Chile, Santiago 8380492, Chile

Facultad de Diseño, Universidad del Desarrollo, Avenida Plaza 680, Las Condes, Santiago 7610658, Chile

Funding

Fondo Nacional de Desarrollo Cient?fico y Tecnol?gico · Fondo de Financiamiento de Centros de Investigaci?n en ?reas Prioritarias · FONDEQUIP

References (70)

Show source-provided references
1. 10.1007/s10924-021-02337-610.1007/s10924-021-02337-6 ↗
2. 10.1007/s10311-018-0763-210.1007/s10311-018-0763-2 ↗
3. Utzeri G. · Colloids Surf., A · 2022 · 63 · 12804410.1016/j.colsurfa.2021.128044 ↗
4. 10.1007/s11164-019-04067-w10.1007/s11164-019-04067-w ↗
5. 10.1016/j.envres.2022.11421410.1016/j.envres.2022.114214 ↗
6. 10.1016/j.molstruc.2021.13061010.1016/j.molstruc.2021.130610 ↗
7. 10.3390/molecules2617519310.3390/molecules26175193 ↗
8. 10.3762/bjoc.16.12710.3762/bjoc.16.127 ↗
9. 10.3390/nano1217290010.3390/nano12172900 ↗
10. 10.1007/s11356-021-15187-510.1007/s11356-021-15187-5 ↗
11. 10.1016/j.ijpharm.2025.12555210.1016/j.ijpharm.2025.125552 ↗
12. 10.1021/acsami.3c1803810.1021/acsami.3c18038 ↗
13. 10.1007/s11164-019-04059-w10.1007/s11164-019-04059-w ↗
14. 10.1016/j.colsurfb.2022.11310110.1016/j.colsurfb.2022.113101 ↗
15. 10.1016/j.jddst.2024.10589310.1016/j.jddst.2024.105893 ↗
16. 10.1007/s10847-024-01263-z10.1007/s10847-024-01263-z ↗
17. 10.1016/j.jddst.2021.10249410.1016/j.jddst.2021.102494 ↗
18. 10.7324/JAPS.2025.23651710.7324/JAPS.2025.236517 ↗
19. 10.1007/s12247-023-09741-610.1007/s12247-023-09741-6 ↗
20. 10.1208/s12249-022-02372-z10.1208/s12249-022-02372-z ↗
21. 10.1016/j.envres.2023.11787010.1016/j.envres.2023.117870 ↗
22. 10.3390/polym1411219910.3390/polym14112199 ↗
23. 10.1016/j.seppur.2024.12907210.1016/j.seppur.2024.129072 ↗
24. 10.3390/polym1707085610.3390/polym17070856 ↗
25. 10.1002/wcms.160610.1002/wcms.1606 ↗
26. 10.1002/jcc.2175910.1002/jcc.21759 ↗
27. 10.1021/jp810292n10.1021/jp810292n ↗
28. 10.1063/1.370015410.1063/1.3700154 ↗
29. 10.1039/D0SC05327A10.1039/D0SC05327A ↗
30. 10.1039/C7CP02110K10.1039/C7CP02110K ↗
31. 10.1002/jcc.2288510.1002/jcc.22885 ↗
32. 10.1038/s41598-023-48603-610.1038/s41598-023-48603-6 ↗
33. 10.1016/j.ijpharm.2019.05.01510.1016/j.ijpharm.2019.05.015 ↗
34. 10.1016/j.ejpb.2009.11.00310.1016/j.ejpb.2009.11.003 ↗
35. 10.1007/s10847-012-0224-710.1007/s10847-012-0224-7 ↗
36. 10.1016/j.ijpharm.2020.11935610.1016/j.ijpharm.2020.119356 ↗
37. 10.3390/pharmaceutics1309135610.3390/pharmaceutics13091356 ↗
38. 10.1080/02726351.2015.108165810.1080/02726351.2015.1081658 ↗
39. 10.1007/s42729-019-00062-710.1007/s42729-019-00062-7 ↗
40. 10.3390/polym1323407310.3390/polym13234073 ↗
41. 10.1016/j.fluid.2022.11344310.1016/j.fluid.2022.113443 ↗
42. 10.2147/IJN.S40553410.2147/IJN.S405534 ↗
43. 10.1002/jrs.428210.1002/jrs.4282 ↗
44. 10.3390/ijms2408754410.3390/ijms24087544 ↗
45. 10.3390/ma1403047810.3390/ma14030478 ↗
46. 10.1016/j.foodchem.2020.12813210.1016/j.foodchem.2020.128132 ↗
47. 10.3390/nano1110248410.3390/nano11102484 ↗
48. 10.3390/pharmaceutics1004016910.3390/pharmaceutics10040169 ↗
49. 10.3390/ma1609353810.3390/ma16093538 ↗
50. 10.1016/j.jddst.2020.10227510.1016/j.jddst.2020.102275 ↗
51. 10.1007/s11164-019-04067-w10.1007/s11164-019-04067-w ↗
52. 10.1016/j.envpol.2020.11619110.1016/j.envpol.2020.116191 ↗
53. 10.1016/j.envpol.2024.12335210.1016/j.envpol.2024.123352 ↗
54. 10.1016/j.scitotenv.2020.14187310.1016/j.scitotenv.2020.141873 ↗
55. 10.3390/ijms2111407910.3390/ijms21114079 ↗
56. 10.3390/app1209418210.3390/app12094182 ↗
57. 10.3390/polym1323411010.3390/polym13234110 ↗
58. 10.1021/acssuschemeng.6b0319110.1021/acssuschemeng.6b03191 ↗
59. 10.1016/j.jphotochem.2021.11328710.1016/j.jphotochem.2021.113287 ↗
60. 10.1016/j.carbpol.2017.06.07410.1016/j.carbpol.2017.06.074 ↗
61. 10.3389/fmicb.2022.90602610.3389/fmicb.2022.906026 ↗
62. 10.1016/j.seppur.2023.12621310.1016/j.seppur.2023.126213 ↗
63. 10.3390/agronomy1512274610.3390/agronomy15122746 ↗
64. 10.1016/j.cej.2022.14088210.1016/j.cej.2022.140882 ↗
65. 10.1007/s11356-022-22501-210.1007/s11356-022-22501-2 ↗
66. 10.1016/j.seppur.2025.13170210.1016/j.seppur.2025.131702 ↗
67. 10.1016/j.talanta.2025.12777310.1016/j.talanta.2025.127773 ↗
68. 10.1080/02508060.2024.234639410.1080/02508060.2024.2346394 ↗
69. 10.1002/chir.2313610.1002/chir.23136 ↗
70. 10.1039/C7AN01324H10.1039/C7AN01324H ↗