Ion-Doped Poly(2-Nitro-1,4-Phenylenediamine) Hollow Nanospheres for Photothermal Therapy
Source abstract
Abstract
Phototherapy of cancer attracted a great deal of attention in recent years, and novel eligible photothermal agent (PTA) with good photostability and excellent photothermal effect is highly needed. Herein, Fe3+-doped poly(2-nitro-1,4-phenylenediamine) hollow spheres were successfully prepared at room temperature via a simple solution-based wet chemical synthesis method. The resultant products exhibited excellent biocompatibility and good photothermal effect. The in vitro and in vivo evaluation demonstrates good cancer cell killing effect and the excellent antitumor efficacy of Fe3+-doped poly(2-nitro-1,4-Phenylenediamine) via photothermal therapy (PTT) for the first time.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Nanoparticle-Based Drug Delivery · Dendrimers and Hyperbranched Polymers
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China
Changchun University of Science and Technology, Changchun 130022, PR China
University of Science and Technology of China, Hefei 230026, PR China
Funding
National Natural Science Foundation of China · Chinese Academy of Sciences · Science and Technology Development Planning Project of Jilin Province
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