Near-Infrared-Emitting Silver Nanoclusters as Fluorescent Probes for Super-resolution Radial Fluctuation Imaging of Lysosomes
Source abstract
Abstract
Because of their remarkable properties like biocompatibility, ultrasmall size, and tunable optical and electronic properties, silver nanoclusters (AgNCs) have been widely explored in numerous biological applications but have rarely been reported for super-resolution microscopy. Herein we present bovine serum albumin-protected AgNCs to specifically stain the lysosomes inside HeLa cells. We resolved a single lysosome with a maximum resolution of ∼126 nm using super-resolution radial fluctuation microscopy. We believe that in the future these clusters can be used as specific markers for other cell organelles and can further assist in the capture of real-time events.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanocluster Synthesis and Applications · Gold and Silver Nanoparticles Synthesis and Applications · Quantum Dots Synthesis And Properties
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
School of Basic Sciences, Indian Institute of Technology (IIT) Mandi, Mandi, Himachal Pradesh 175075, India
BioX Centre, Indian Institute of Technology (IIT) Mandi, Mandi, Himachal Pradesh 175075, India
Advanced Materials Research Centre (AMRC), Indian Institute of Technology (IIT) Mandi, Mandi, Himachal Pradesh 175075, India
Funding
Council of Scientific and Industrial Research · Science and Engineering Research Board
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