Exploiting Inherent Instability of 2D Black Phosphorus for Controlled Phosphate Release from Blow-Spun Poly(lactide-co-glycolide) Nanofibers
Source abstract
Abstract
Efforts have been made to stabilize black phosphorus (BP) to utilize its tunable band gap and anisotropic mechanical properties. Here, the intrinsic instability of BP is exploited for controlled therapeutic ion release, namely phosphate. BP was incorporated into degradable poly(lactide-co-glycolide) fibers via solution blow spinning. Raman spectroscopy confirmed the incorporation of 2D-BP into the nanocomposite along with ICP-AES. It was also demonstrated that modifying the initial loading of 2D-BP in the PLGA fibers permitted tunable release rates of phosphate ions over an 8 week in vitro study.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: 2D Materials and Applications · MXene and MAX Phase Materials · Graphene and Nanomaterials Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Bio-Active Materials Group, School of Materials, The University of Manchester, MSS Tower, Manchester M13 9PL, U.K.
Materials and Biosystems Laboratory (LAMAB), Department of Materials Engineering (DEMat), Federal University of Paraíba (UFPB), CEP58051-900 João Pessoa, PB, Brazil
School of Chemistry, University of Manchester, Oxford Road, Manchester M13 9PL, U.K.
Department of Biomaterials, Institute of Clinical Dentistry, University of Oslo, P.O. Box 1109, Blindern, 0317 Oslo, Norway
School of Materials, University of Manchester, Manchester M13 9PL, U.K.
Funding
Engineering and Physical Sciences Research Council · Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico · Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior · Oslo Regenerative Medicine Cluster, Oslo University Hospital
References (61)
Show source-provided references
1. 10.1016/j.matchemphys.2016.12.01410.1016/j.matchemphys.2016.12.014 ↗
2. 10.1103/PhysRevB.91.11543610.1103/PhysRevB.91.115436 ↗
3. 10.1002/smll.20170283010.1002/smll.201702830 ↗
4. 10.1038/ncomms956310.1038/ncomms9563 ↗
5. 10.1016/j.micromeso.2016.01.03110.1016/j.micromeso.2016.01.031 ↗
6. 10.1039/C7RA00160F10.1039/C7RA00160F ↗
7. 10.7150/thno.2257310.7150/thno.22573 ↗
8. 10.1016/j.biomaterials.2016.03.02210.1016/j.biomaterials.2016.03.022 ↗
9. 10.1038/nnano.2014.3510.1038/nnano.2014.35 ↗
10. 10.1002/adma.20140515010.1002/adma.201405150 ↗
11. 10.1021/jacs.5b0602510.1021/jacs.5b06025 ↗
12. 10.1039/C4CC05752J10.1039/C4CC05752J ↗
13. 10.1038/s41467-017-00358-110.1038/s41467-017-00358-1 ↗
14. 10.1063/1.488521510.1063/1.4885215 ↗
15. 10.1209/0295-5075/112/3700310.1209/0295-5075/112/37003 ↗
16. 10.1002/smll.20160289610.1002/smll.201602896 ↗
17. 10.1002/adma.20170561110.1002/adma.201705611 ↗
18. 10.1073/pnas.171442111510.1073/pnas.1714421115 ↗
19. 10.1002/anie.20150615410.1002/anie.201506154 ↗
20. 10.1002/adma.20160327610.1002/adma.201603276 ↗
21. 10.1002/adfm.20170195510.1002/adfm.201701955 ↗
22. 10.1002/adma.20170345810.1002/adma.201703458 ↗
23. 10.1039/C6RA21296D10.1039/C6RA21296D ↗
24. 10.1021/acsnano.5b0114310.1021/acsnano.5b01143 ↗
25. 10.1021/nl500654210.1021/nl5006542 ↗
26. 10.1016/j.actbio.2014.11.00410.1016/j.actbio.2014.11.004 ↗
27. 10.1016/j.biomaterials.2003.11.01210.1016/j.biomaterials.2003.11.012 ↗
28. 10.1080/1537649059092861510.1080/15376490590928615 ↗
29. 10.1007/s10853-017-0868-110.1007/s10853-017-0868-1 ↗
30. 10.1016/j.actbio.2012.08.02310.1016/j.actbio.2012.08.023 ↗
31. 10.1016/j.biomaterials.2003.10.03610.1016/j.biomaterials.2003.10.036 ↗
32. 10.1016/j.biomaterials.2003.08.00710.1016/j.biomaterials.2003.08.007 ↗
33. 10.1016/j.biomaterials.2006.02.03610.1016/j.biomaterials.2006.02.036 ↗
34. 10.1016/j.biomaterials.2007.08.02910.1016/j.biomaterials.2007.08.029 ↗
35. 10.1089/ten.2005.11.107710.1089/ten.2005.11.1077 ↗
36. 10.1038/ncomms1296710.1038/ncomms12967 ↗
37. 10.1002/app.3027510.1002/app.30275 ↗
38. 10.1021/acsami.6b1299410.1021/acsami.6b12994 ↗
39. Boss C. B. · 1999
40. 10.1021/nn501226z10.1021/nn501226z ↗
41. 10.1039/C6CC03206K10.1039/C6CC03206K ↗
42. 10.1038/nnano.2016.17110.1038/nnano.2016.171 ↗
43. 10.3390/ijms1503364010.3390/ijms15033640 ↗
44. 10.4012/dmj.2011-18210.4012/dmj.2011-182 ↗
45. 10.1016/j.biomaterials.2005.08.01610.1016/j.biomaterials.2005.08.016 ↗
46. 10.1039/C6TB02083F10.1039/C6TB02083F ↗
47. 10.1016/j.biomaterials.2006.06.02810.1016/j.biomaterials.2006.06.028 ↗
48. 10.1016/j.supflu.2012.03.01610.1016/j.supflu.2012.03.016 ↗
49. 10.1016/j.ijpharm.2017.05.03810.1016/j.ijpharm.2017.05.038 ↗
50. 10.1155/2013/40957210.1155/2013/409572 ↗
51. 10.1088/1748-6041/11/3/03500110.1088/1748-6041/11/3/035001 ↗
52. 10.1016/j.apmt.2016.05.00110.1016/j.apmt.2016.05.001 ↗
53. 10.1021/acsami.7b1357210.1021/acsami.7b13572 ↗
54. 10.1039/C7NR00663B10.1039/C7NR00663B ↗
55. 10.1038/nnano.2015.7110.1038/nnano.2015.71 ↗
56. 10.1039/C6NR04773D10.1039/C6NR04773D ↗
57. 10.1038/s41598-017-02474-w10.1038/s41598-017-02474-w ↗
58. 10.3390/polym303137710.3390/polym3031377 ↗
59. 10.1089/dia.2011.005010.1089/dia.2011.0050 ↗
60. 10.1016/j.jconrel.2012.10.01510.1016/j.jconrel.2012.10.015 ↗
61. 10.1016/j.polymdegradstab.2016.10.01710.1016/j.polymdegradstab.2016.10.017 ↗