journal article·2025-07-25Open access

Thermoregulable Magnetic Microfluidic Devices by Magnetic Hyperthermia from Iron Oxide Nanoparticles

Santiago Parames-Estevez, Pelayo García-Acevedo, Yago Radziunas-Salinas, Yolanda Piñeiro, José Rivas, Maria Teresa Flores-Arias, Alberto P. Munuzuri

ACS Applied Nano Materials· Volume 8· Issue 29

Abstract

Accurate control of energy supplied to a liquid in a controlled environment is essential for automating and optimizing processes. Organs on a chip (OoC) are an emerging technology that allows the design of customized environmental conditions for cells and chemical reactions by creating specific channel shapes while simplifying data acquisition. To thermoregulate these devices and therefore expand their use widely, we integrated iron oxide nanoparticles (IONPs) within the matrix of the chip to heat them by using magnetic hyperthermia. We tested the devices and developed a digital twin that reproduces the experimental OoC-fluid interaction while allowing us to measure parameters that would be inaccessible in a laboratory and get a full picture of the heat transfer at the boundary.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Characterization and Applications of Magnetic Nanoparticles · Microfluidic and Bio-sensing Technologies · Electrohydrodynamics and Fluid Dynamics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Group of Non-Linear Physics. Campus Sur. University of Santiago de Compostela

Galician Center for Mathematical Research and Technology (CITMAga)

Nanotechnology and Magnetism Lab─NANOMAG, Materials Institute−iMATUS, Health Research Institute−IDIS, Department of Applied Physics

Universidade de Santiago de Compostela.

Photonics4Life Research Group, Applied Physics Department, Faculty of Physics and Materials Institute - iMATUS, Universidade de Santiago de Compostela, Campus Vida, Santiago de Compostela 15782, Spain

Funding

Ministerio de Ciencia, Innovaci?n y Universidades · Agencia Estatal de Investigaci?n · European Regional Development Fund · Axencia Galega de Innovaci?n · Xunta de Galicia

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