journal article·2024-12-13

Ag-Doped SnSe Nanosheets for Enhanced NIR-II Light-Induced Apoptosis

Dequan Xiao, Yan Gong, Jing Zhang, Hui Liu, Lile Dong

ACS Applied Nano Materials· Volume 7· Issue 23
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Abstract

Triple-negative breast cancer (TNBC) is one of the most aggressive and challenging subtypes with limited treatment options and poor prognosis. To overcome these obstacles, Ag-doped SnSe (ASS) nanosheets were used as photonic hyperthermia agents for treating TNBC. ASS featured a high photothermal-conversion efficiency and photon hyperthermia effect. Additionally, biosafety assessments, including hemolysis assays and histopathological analysis, confirmed that ASS was biosafety. These findings suggest that ASS, in synergy with the second near-infrared biowindow (NIR-II) light irradiation, offers a noninvasive, effective, and safe therapeutic strategy for TNBC. This innovative approach exemplifies the evolving landscape of TNBC treatment, where technology and biology converge to offer more precise and personalized therapies.
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Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis · Spectroscopy Techniques in Biomedical and Chemical Research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Ganzhou Women and Children’s Health Care Hospital, Ganzhou 341000, China

Gannan Health Vocational College, Ganzhou 341000, China

Ganjiang Innovation Academy, Chinese Academy of Sciences, Ganzhou 341000, China

Funding

Bureau of Science and Technology of Ganzhou Municipality · Health Commission of Jiangxi Province · Natural Science Foundation of Jiangxi Province

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